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首页> 外文会议>Annual Conference on Information Sciences and Systems >The physical language of molecular codes: A rate-distortion approach to the evolution and emergence of biological codes
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The physical language of molecular codes: A rate-distortion approach to the evolution and emergence of biological codes

机译：分子码的物理语言：生物学规范演化和出现的速率变形方法

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The function of the organism hinges on the performance of its information-processing networks, which convey information via molecular recognition. Many paths within these networks utilize molecular codebooks, such as the genetic code, to translate information written in one class of molecules into another molecular "language". The present paper examines the emergence and evolution of molecular codes in terms of rate-distortion theory and reviews recent results of this approach. We discuss how the biological problem of maximizing the fitness of an organism by optimizing its molecular coding machinery is equivalent to the communication engineering problem of designing an optimal information channel. The fitness of a molecular code takes into account the interplay between the quality of the channel and the cost of resources which the organism needs to invest in its construction and maintenance. We analyze the dynamics of a population of organisms that compete according to the fitness of their codes. The model suggests a generic mechanism for the emergence of molecular codes as a phase transition in an information channel. This mechanism is put into biological context and demonstrated in a simple example.
机译：有机体铰链对其信息处理网络的性能，通过分子识别来传达信息。这些网络内的许多路径利用分子码本，例如遗传密码，将在一类分子中写入另一种分子“语言”的信息。本文探讨了在速率 - 畸变理论方面的出现和演变，并评论了这种方法的最近结果。我们讨论通过优化其分子编码机械来最大化生物体的健身性的生物学问题是等同于设计最佳信息信道的通信工程问题。分子代码的适应性考虑了渠道质量与有机体需要投资其建设和维护的资源成本之间的相互作用。我们分析了根据其代码的适应性竞争的生物群体的动态。该模型表明了作为信息信道中的相位转换的分子代码出现的通用机制。该机制被纳入生物学背景下，并在一个简单的例子中证明。

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