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首页> 外文会议>Conference on Biomedical Applications in Molecular, Structural, and Functional Imaging >Early classification of Alzheimer's disease using hippocampal texture from structural MRI
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Early classification of Alzheimer's disease using hippocampal texture from structural MRI

机译：使用结构MRI的海马纹理早期分类阿尔茨海默病

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Convergent evidence has been collected to support that Alzheimer's disease (AD) is associated with reduction in hippocampal volume based on anatomical magnetic resonance imaging (MRI) and impaired functional connectivity based on functional MRI. Radiomics texture analysis has been previously successfully used to identify MRI biomarkers of several diseases, including AD, mild cognitive impairment and multiple sclerosis. In this study, our goal was to determine if MRI hippocampal textures, including the intensity, shape, texture and wavelet features, could be served as an MRI biomarker of AD. For this purpose, the texture marker was trained and evaluated from MRI data of 48 AD and 39 normal samples. The result highlights the presence of hippocampal texture abnormalities in AD, and the possibility that texture may serve as a neuroimaging biomarker for AD.
机译：收集了收敛证据​​以支持阿尔茨海默病（AD）与基于解剖磁共振成像（MRI）和基于功能性MRI的功能连通性受损的海马体积减少相关。以前已经成功地识别若干疾病的MRI生物标志物，包括广告，轻度认知障碍和多发性硬化症。在这项研究中，我们的目标是确定MRI海马纹理，包括强度，形状，质地和小波特征，可以作为广告的MRI生物标志物。为此目的，从48个AD和39正常样品的MRI数据培训和评估纹理标记。结果突出了广告中海马纹理异常的存在，并且质地可以用作广告的神经影像生物标志物的可能性。

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