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The role of intracellular calcium in apoptosis of human breast and oral cancer cells induced by nanosecond pulsed electric fields

机译:细胞内钙在纳秒脉冲电场诱导人乳腺癌细胞凋亡中的作用

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Many previous studies have reported the interesting facts that nanosecond pulsed electrical fields (nsPEF) could reduce tumors on mice, and there have been a few hypotheses on apoptosis pathways that induced by nsPEF. However the apoptosis mechanism has not fully been elucidated so far. In this study, we investigated the relationship between intracellular calcium burst and apoptosis of breast cancer cell MCF-7 and Oral squamous cell carcinoma (OSCC) cell Cal-27 after nsPEF treatment.
机译:许多先前的研究报告了纳秒脉冲电场(NPEF)可以减少小鼠肿瘤的有趣事实,并且有几个假设由NPEF诱导的凋亡途径。然而,到目前为止,凋亡机制尚未完全阐明。在这项研究中,我们研究了NPSP处理后乳腺癌细胞MCF-7和口腔鳞状细胞癌(OSCC)细胞癌(OSCC)细胞CAL-27之间的内钙爆发和凋亡之间的关系。

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