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首页> 外文会议>SPIE Medical Imaging Conference >Mechanically assisted 3D ultrasound with geometrically variable imaging for minimally invasive focal liver tumor therapy
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Mechanically assisted 3D ultrasound with geometrically variable imaging for minimally invasive focal liver tumor therapy

机译：用几何可变成像机械辅助三维超声，用于微创局灶性肝肿瘤疗法

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Liver cancer is the second and sixth most frequent cause of cancer mortality worldwide in men and women, respectively,with high prevalence in under developed and developing countries. Minimally invasive focal ablation of liver tumors isan alternative technique to resection and transplantation for early-stage cancer and is focused on reducing patientcomplications and recovery times. Although promising, the therapeutic benefits are currently present with high local cancerrecurrence. One potential source of error arises when performing therapy applicator guidance with 2D ultrasound (US)since the field-of-view is limited and requires the physician to build a mental image of the anatomy. Our solution to thislimitation has been the development of a novel mechanically assisted 3D US imaging and guidance system capable ofproviding geometrically variable images.A three-motor mechanical mover was designed to provide linear, tilt, and hybrid geometries with adjustable ranges ofmotion for variable 3D US fields-of-view. This mover can manipulate any clinically available 2D US transducer viatransducer-specific 3D-printed holders to guide applicator insertions intraoperatively. This mover is held by acounterbalanced mechanical “arm and wrist”, which contain electromagnetic brakes and five encoders to track the positionof the transducer. This mechanical support is mounted on a portable cart with coarse adjustable height to accommodategross differences in patient sizes. This work represents the design, construction, software implementation, preliminary 3Dvolume reconstruction evaluation, and the first qualitative human volunteer scans. Geometric errors performed on a gridphantom were <3% and human volunteer images were clinically applicable.
机译：肝癌是男女癌症死亡率的第二次和第六次最常见的原因，发达国家和发展中国家患病率较高。肝脏肿瘤的微创局灶性消融是早期癌症切除和移植的替代技术，重点是减少患者并发症和恢复时间。虽然有希望，目前患有高地癌症的治疗益处再次发生。使用2D超声（US）进行治疗施用器引导时出现一种潜在的误差来源由于视野是有限的，并且需要医生建立解剖学的心理形象。我们解决方案限制是一种新颖的机械辅助3D美国成像和引导系统的开发提供几何可变图像。设计了一种三电机机械动机，以提供具有可调节范围的线性，倾斜和混合形象Motion for可变3D美国视野视图。该移动器可以通过临床可用的2D换能器进行操纵换能器特定的3D印刷保持器以引导施用涂抹器插入。这个搬家者被A举行了平衡机械“手臂和手腕”，包含电磁制动器和五个编码器，以跟踪位置换能器。这种机械支撑安装在具有粗调高度的便携式推车上以容纳患者尺寸的粗略差异。这项工作代表了设计，施工，软件实现，初步3D批量重建评估，以及第一个定性人类志愿者扫描。在网格上执行的几何错误幻影<3％，人类志愿者图像在临床上适用。

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