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Cold Temperature and Risk of Death Due to Stroke

机译:寒冷的温度和由于中风而死亡的风险

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Objective: Temperature is associated with the risk of death due to myocardial infarction, but the relationship with cerebrovascular events is poorly understood. We evaluated the association between cold temperature and the risk of death due to haemorrhagic or ischemic stroke. Methods: Using data from provincial death registration certificates, we undertook a case-crossover study to investigate the association between cold temperature and death due to stroke during 1981-2013 in Quebec, Canada. We selected deaths between November and April, the coldest months of the year, and paired them to the temperature data. Temperature data were obtained from Environment Canada monitoring stations for each of the 18 health regions in Quebec. We used conditional logistic regression to compute odds ratios (OR) and 95% confidence intervals (CI) for the association between minimum daily temperature and haemorrhagic and ischemic stroke. Models were adjusted for the duration and quantity of snowfall. Results: There were 13,208 deaths due to haemorrhagic stroke, and 16,383 due to ischemic stroke during the study. The risk of death from haemorrhagic stroke was elevated on cold days as well as the following day. Compared with 0°C, a minimum temperature of -30°C was associated with an OR of 1.22 (95% CI 1.08-1.38) for haemorrhagic stroke the day of exposure, and an OR of 1.18 (95% CI 1.04-1.33) the day following exposure. Associations were weaker and not statistically significant for ischemic stroke. Conclusion: Cold temperature was associated with risk of death due to haemorrhagic stroke. In the context of climate change and a greater frequency of extreme winter events, individuals with predisposing risk factors should be aware of the higher risk of death due to haemorrhagic stroke during cold temperature. Environmental alerts targeting populations at risk, including recommendations to minimize exposure during extreme cold, may be merited.
机译:目的:温度与心肌梗死导致的死亡风险有关,但与脑血管事件的关系很难理解。我们评估了寒冷温度与由于出血性或缺血性脑卒中的死亡风险之间的关联。方法:使用省级死亡登记证书的数据,我们进行了一个案例交叉研究,探讨加拿大魁北克省1981 - 2013年寒冷温度和死亡之间的关联。我们在11月至4月之间选择了死亡,今年最冷的几个月,并将它们与温度数据配对。温度数据是从魁北克省18个卫生地区中的每一个的环境加拿大监测站获得的。我们使用有条件的逻辑回归来计算最低日常温度和出血性和缺血性卒中之间的关联的大量比率(或)和95%的置信区间(CI)。调整模型的降雪量和数量。结果:出血性脑卒中引起的13,208例死亡率,16,383年由于缺血性脑卒中。血液中风中死亡的风险在寒冷的日子以及第二天升高。与0°C相比,-30℃的最小温度与140℃或1.22(95%CI 1.08-1.38)相关,用于曝光当天的出血性中风,AN或1.18(95%CI 1.04-1.33)接触后的一天。缺血性卒中的关联较弱,并且没有统计学意义。结论:寒冷温度与由于出血性卒中引起的死亡风险有关。在气候变化和极端冬季事件的更大频率的背景下,具有易受风险因素的个体应该意识到寒冷温度血液中风引起的死亡风险较高。针对风险的环境警报,包括在极端寒冷期间最小化暴露的建议,包括建议。

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