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Laser-fluorescent pulses as a probe to brain energy and efficiency

机译:激光荧光脉冲可探测大脑的能量和效率

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Abstract: A specific electrode was made of quartz optic fibers with a thin metal membrane, the quartz core guided nitrogen laser beam (10 - 40 $mu@j/pulse, I pulse/sec.) into brain cortex, and got out fluorescent pulses emitted by brain NADH and FAD moleculars. The amplitudes of laser-fluorescent pulses represented brain NADH and FAD concentrations determined by HPLC methods. The metal membrane outside optic fiber (1*10 $mu@m$+2$/, 40 mm long) as a specific electrode recorded neural discharges. The neural pulses represented neuron activities. The ratio of frequency changes of neural discharges to the amplitude changes of laser-fluorescent pulses was written as $eta $EQ dF$- i$//dA$-i$/, which $eta means neuron efficiency. The results showed that intensity of nitrogen beam increased the amplitudes of laser-fluorescent pulses and decreased the $eta value. Electric stimuli increased the frequency of neural discharges and increased the $eta value. The results mean that low power laser beam guided into brain by optic fibers can work as a stimulant factor as well as a probe to brain function.!13
机译:摘要:用具有金属薄膜的石英光纤制成特定电极,石英芯将氮气激光束(10-40 $ mu @ j / pulse,I脉冲/秒)引导到大脑皮层,并发出荧光脉冲。由大脑NADH和FAD分子发出。激光荧光脉冲的振幅代表通过HPLC方法测定的大脑NADH和FAD浓度。光纤外部的金属膜(1 *10μm$ m + 2 $ /,长40mm)作为特定电极记录了神经放电。神经脉冲代表神经元活动。神经放电的频率变化与激光荧光脉冲的幅度变化之比记为$ eta $ EQ dF $-i $ // dA $ -i $ /,这意味着神经元效率。结果表明,氮气束的强度增加了激光荧光脉冲的幅度,并降低了η值。电刺激增加了神经放电的频率并增加了$ eta值。结果表明,光纤将低功率激光束引导到大脑中既可以作为刺激因素,也可以作为对大脑功能的探查。13

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