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Numerical Simulation of Dielectrophoresis Induced Electrothermal Fluid Flow

机译:介电泳诱导电热流体流动的数值模拟

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摘要

Dielectrophoresis (DEP) based microdevices offer a great number of significant advantages for the manipulation of biological particles such as cells, bacteria, viruses and DNA over traditional methods. To enable successfully dielectrophoretic manipulation of biological particles, electric fields of higher intensity need to be generated in order to increase the DEP forces. However, the introduced electric field may cause the joule heating effect and thermal denaturation of biological particles. This paper presents a numerical solution of the DEP force and the resulting electrical electrothermal driven fluid flow on a DEP microdevice. Theoretical investigations were made about the impact of electrothermal flow on DEP based microdevice. The fluid field was solved by coupling electrical, thermal, and mechanical equations. It is shown that under some typical experimental conditions of DEP based manipulation of biological particles, it is necessary to consider the possible influence of the electrothermal flow.
机译:与传统方法相比,基于介电电泳(DEP)的微设备为操纵生物粒子(例如细胞,细菌,病毒和DNA)提供了许多重要优势。为了成功地进行生物颗粒的介电泳操作,需要产生更高强度的电场以增加DEP力。然而,引入的电场可能引起焦耳热效应和生物颗粒的热变性。本文提出了DEP力以及在DEP微型设备上产生的电热驱动流体流动的数值解。对电热流对基于DEP的微型设备的影响进行了理论研究。通过耦合电,热和机械方程来求解流场。结果表明,在基于DEP的生物颗粒处理的一些典型实验条件下,有必要考虑电热流的可能影响。

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