首页> 外文会议>MRS spring meeting symposium >Biologically Engineered Quantum Dots for Biomedical Applications
【24h】

Biologically Engineered Quantum Dots for Biomedical Applications

机译:生物工程应用的生物工程量子点

获取原文

摘要

We report on a short-wavelength, 'blue' spectral shift of the photoluminescence (PL) spectrum in CdSeTe/ZnS core/shell quantum dots (QDs) caused by bioconjugation with several monoclonal cancer related antibodies (ABs). Scanning PL spectroscopy was performed on samples dried on solid substrates at various temperatures. The influence of the AB chemical origin on the PL spectral shift was observed. The conjugation QD-AB reaction was confirmed using the agarose gel electrophoresis technique. The spectral shift is strongly increased and the process facilitated when the samples are dried above room temperature. The PL spectroscopic mapping revealed a profile of the PL spectral shift across the dried QD-AB spot. Transmission Electron Microscopy analyses of the samples were performed to reveal the shape and size of individual QDs. A mechanism of the 'blue' shift is attributed to changes in the QD electronic energy levels caused by local stress field applied to the bio-conjugated QD.
机译:我们报告了CdSeTe / ZnS核/壳量子点(QDs)中的光致发光(PL)光谱的短波“蓝”光谱位移,这是由与几种单克隆癌症相关抗体(ABs)的生物缀合引起的。在各种温度下对在固体基质上干燥的样品进行扫描PL光谱分析。观察到AB化学来源对PL光谱位移的影响。使用琼脂糖凝胶电泳技术确认了共轭QD-AB反应。当样品在室温以上干燥时,光谱偏移会大大增加,并且有助于简化该过程。 PL光谱图显示了干燥QD-AB点上PL光谱位移的轮廓。对样品进行了透射电子显微镜分析,以揭示单个量子点的形状和大小。 “蓝”移的机制归因于由施加到生物共轭QD的局部应力场引起的QD电子能级变化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号