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首页> 外文会议>Nanobiosystems: Processing, characterization, and applications VIII >Creation of Carbon Nanotube Based BioSensors through Dielectrophoretic Assembly
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Creation of Carbon Nanotube Based BioSensors through Dielectrophoretic Assembly

机译：通过介电泳组装创建基于碳纳米管的生物传感器

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Due to their excellent electrical, optical, and mechanical properties, nanosized single wall carbon nanotubes (SWNTs) have attracted significant attention as a transducing element in nano-bio sensor research. Controlled assembly, device fabrication, and bio-functionalization of the SWNTs are crucial in creating the sensors. In this study, working biosensor platforms were created using dielectrophoretic assembly of single wall carbon nanotubes (SWNTs) as a bridge between two gold electrodes. SWNTs in a commercial SDS surfactant solution were dispensed in the gap between the two gold electrodes, followed by applying an ac voltage across the two electrodes. The dielectrophoresis aligns the CNTs and forms a bridge between the two electrodes. A copious washing and a subsequent annealing of the devices at 200 °C remove the surfactants and create an excellent semiconducting (p-type) bridge between the two electrodes. A liquid gated field effect transistor (LGFET) was built using DI water as the gate dielectric and the SWNT bridge as the channel. Negative gate voltages of the FET increased the drain current and applying a positive gate voltage of+0.5V depleted the channel of charges and turned the device off. The biosensor was verified using both the two terminal and three terminal devices. Genomic salmon DNA dissolved in DI water was applied on the SWNT bridge in both type of devices. In the two terminal device, the conductance of the bridge dropped by 65x after the binding of the DNA. In the LGFET, the transconductance of the device decreased 2X after the binding of the DNA. The binding of the DNA also suppressed hysteresis in the Drain Current vs Gate Voltage characteristics of the LGFET.
机译：纳米级单壁碳纳米管（SWNT）由于其出色的电，光学和机械性能，作为纳米生物传感器研究中的一种转导元素，引起了广泛的关注。 SWNT的受控组装，设备制造和生物功能化对于创建传感器至关重要。在这项研究中，使用单壁碳纳米管（SWNT）的介电泳组装作为两个金电极之间的桥梁，创建了有效的生物传感器平台。将商用SDS表面活性剂溶液中的SWNT分配到两个金电极之间的间隙中，然后在两个电极之间施加交流电压。介电泳使CNT对准并在两个电极之间形成桥。大量清洗并随后在200°C下对设备进行退火，可以去除表面活性剂，并在两个电极之间形成出色的半导体（p型）电桥。使用去离子水作为栅极电介质和SWNT桥作为沟道，构建了液控栅极场效应晶体管（LGFET）。 FET的负栅极电压增加了漏极电流，施加+ 0.5V的正栅极电压会耗尽电荷通道，并关闭器件。使用两个终端设备和三个终端设备对生物传感器进行了验证。将溶解在去离子水中的基因组鲑鱼DNA应用于两种类型的设备的SWNT桥上。在两个终端设备中，DNA结合后，电桥的电导下降了65倍。在LGFET中，与DNA结合后，器件的跨导降低了2倍。 DNA的结合还抑制了LGFET的漏极电流与栅极电压特性之间的磁滞现象。

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