【24h】

Chemical nanoscopy of cell-like membranes

机译:细胞膜的化学纳米分析

获取原文
获取原文并翻译 | 示例

摘要

We have set-up a scanning near-field infrared microscope (SNIM) with widely tunable lasers for label-free molecule identification by infrared spectral fingerprints. The lateral resolution is as low as 30 nm corresponding to the nanotip curvature radius. We obtained infrared spectra from nanoscale sections of self-assembled monolayers (SAM) with volumes as small as 0.01 attoliter corresponding to less than 30000 molecules. Spectroscopy of lipid bilayer stacks on mica revealed nanoscale near-field depth resolution of 80 to 120 nm. We discuss combined systems of membrane proteins and lipids on SAM supports approaching cell like membrane structures. We report on the progress of the set-up of an infrared and terahertz near-field microscope for the new synchrotron beam line at ANKA for full spectral nanoscale information retrieval.
机译:我们已经建立了带有可广泛调谐激光器的扫描近场红外显微镜(SNIM),用于通过红外光谱指纹识别无标签的分子。对应于纳米尖端曲率半径的横向分辨率低至30 nm。我们从自组装单分子层(SAM)的纳米级部分获得了红外光谱,其体积小至0.01 attoliter,对应于少于30000个分子。云母上的脂质双层堆叠的光谱学揭示了80至120 nm的纳米级近场深度分辨率。我们讨论SAM上的膜蛋白和脂质的组合系统支持接近细胞的膜结构。我们报告了在ANKA上用于全光谱纳米级信息检索的新型同步加速器光束线的红外和太赫兹近场显微镜的建立进度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号