Recurrent RNA motifs

机译：循环RNA模式

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Single-stranded regions of structured RNAs often participate in complex interactions involving non-canonical basepairs. A dictionary of isosteric pairings that substitute for each other while preserving the 3D structure of conserved motifs can be inferred from phylogenetic analysis of conserved internal loops for which high-resolution structures also exist, such as loop E of 5S rRNA and the sarcin/ricin loop of 23S rRNA. Such dictionaries of isosteric, context-specific pairings allow one to identify occurrences of the same motif in other molecules.

机译：结构化RNA的单链区域通常参与涉及非规范碱基对的复杂相互作用。可以通过对保守的“内部环”（也存在高分辨率结构，例如5S rRNA的环E和5S rRNA的环）进行系统进化分析，推断出在保持保守基序3D结构的同时相互替代的等距配对字典。 sarcin / ricin环的23S rRNA。这样的，等距的，上下文相关的配对的“词典”允许人们识别其他分子中相同基序的出现。

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《NATO Advanced Research Workshop on RNA Biochemistry and Biotechnology Poznan, Poland October 10-17, 1998》|1998年|p.45-61|共17页
会议地点 Poznan(PL)
作者
N.B. Leontis; E. Westhof;
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正文语种 eng
中图分类生物化学;
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4. Recurrent RNA motifs [C] . N.B. Leontis, E. Westhof NATO advanced research workshop on RNA biochemistry and biotechnology . 1999

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Recurrent RNA motifs

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