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INJECTABLE BIODEGRADABLE MATERIALS FOR ORTHOPAEDIC TISSUE ENGINEERING

机译:骨组织工程中可注射的生物可降解材料

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摘要

The large number of orthopaedic procedures performed each year, including many performed arthroscopically, has led to great interest in injectable biodegradable materials for regeneration of bone and cartilage. A variety of materials have been developed for these applications, including ceramics, naturally-derived substances and synthetic polymers. These materials demonstrate overall biocompatibility and appropriate mechanical properties, as well as promote tissue formation, thus providing an important step towards minimally invasive orthopaedic procedures. This review provides a comparison of these materials based on mechanical properties, biocompatibility and regeneration efficacy. Advantages and disadvantages of each material are explained and design criteria for injectable biodegradable systems are provided.
机译:每年进行的大量整形外科手术,包括许多通过关节镜进行的整形外科手术,引起了人们对可注射生物降解材料用于骨骼和软骨再生的极大兴趣。已经为这些应用开发了多种材料,包括陶瓷,天然来源的物质和合成聚合物。这些材料证明了整体生物相容性和适当的机械性能,并促进了组织的形成,因此为迈向微创骨科手术提供了重要的一步。这篇综述基于机械性能,生物相容性和再生功效对这些材料进行了比较。解释了每种材料的优缺点,并提供了可注射生物降解系统的设计标准。

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