• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>NEA No.4311; Workshop on Computing Radiation Dosimetry(CRD 2002); 20020622-23; Sacavem(PT) >TRACK STRUCTURE SIMULATION: A BASIC TOOL FOR MOLECULAR RADIATION BIOLOGY AND NANODOSIMETRY
【24h】

TRACK STRUCTURE SIMULATION: A BASIC TOOL FOR MOLECULAR RADIATION BIOLOGY AND NANODOSIMETRY

机译：轨迹结构模拟：分子辐射生物学和纳米剂量学的基本工具

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

As is well known from radiation chemistry, the kinetics of radiation-induced systems strongly depends on the distribution of atomic or molecular species produced by primary interactions of ionising radiation in matter or, and this is the same, on the particle track structure. Far-reaching consequences can also be expected, therefore, if biological systems are exposed to ionising radiation, the more so as the radiation-sensitive parts of such systems are located inside highly structured cells. In consequence, the knowledge of track structure is one of the prerequisites for a deeper understanding of radiation-induced effects in radiation chemistry and radiation biology. After a short overview of basic physical aspects of the track structure of electrons, photons and light ions (protons, α-particles, carbon ions) in liquid water, a few consequences of their radiation interaction in nanometric volumes are discussed, which can be related to radiation damage within segments of the DNA molecule and to bio-effect cross-sections of mammalian cells for ionising particles. Here, special emphasis is laid on the stochastic nature of ionisation cluster-size formation in liquid water and on its potential application in nanodosimetric measurements.
机译：从辐射化学众所周知，辐射诱导系统的动力学在很大程度上取决于物质中电离辐射的主要相互作用产生的原子或分子种类的分布，或者与粒子轨道结构相同。因此，如果将生物系统暴露于电离辐射下，则还可能产生深远的后果，因为此类系统的辐射敏感部分位于高度结构化的细胞内。因此，对轨道结构的了解是深入了解辐射化学和辐射生物学中的辐射诱导效应的先决条件之一。在简要概述了液态水中电子，光子和轻离子（质子，α粒子，碳离子）的轨道结构的基本物理方面之后，讨论了它们在纳米体积中的辐射相互作用的一些后果，这可能是相关的破坏DNA分子片段内的辐射损伤，并破坏哺乳动物细胞的电离截面以使粒子电离。在这里，特别强调的是液态水中电离簇大小形成的随机性及其在纳米剂量测量中的潜在应用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号