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首页> 外文会议>Neural Information Processing pt.1; Lecture Notes in Computer Science; 4232 >Analysis of Dynamics of Cultured Neuronal Networks Using I F Model
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Analysis of Dynamics of Cultured Neuronal Networks Using I F Model

机译：使用I和F模型分析培养的神经元网络的动力学

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摘要

Experimentally, spontaneous activity of the developing cultured neuronal networks of cortical neurons is known to show three different types of dynamics according to their developmental stages. As these changes of dynamics play an important role in development of the networks, it is necessary to explore the mechanism of these changes of dynamics for understanding how the networks develop. However, little is known concerning the mechanism from the experiments because of difficulties in controlling experimental conditions. The simulation of electrical activity of neuronal networks formed by simple integrated and fire neurons provide a useful method for exploring such changes of dynamics. The simulation suggests that these changes of dynamics were mainly due to development of connectivity of synapses, changes of relative refractory period and development of inhibitory synapses.
机译：在实验上，皮质神经元的培养神经元网络的自发活动根据其发育阶段显示出三种不同类型的动力学。由于动力学的这些变化在网络的发展中起着重要的作用，因此有必要探索动力学的这些变化的机制，以了解网络的发展方式。但是，由于难以控制实验条件，因此对于实验的机理知之甚少。由简单的集成神经元和火神经元形成的神经元网络的电活动模拟为探索这种动力学变化提供了一种有用的方法。模拟表明，动力学的这些变化主要归因于突触的连通性发展，相对不应期的变化和抑制性突触的发展。

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