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首页> 外文会议>Optical Coherence tomography and coherence domain optical methods in biomedicine XIX >A wide angle low coherence interferometry based eye length optometer
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A wide angle low coherence interferometry based eye length optometer

机译：基于广角低相干干涉法的眼长验光仪

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摘要

Interest in eye growth regulation has burgeoned with the rise in myopia prevalence world-wide. Eye length and eye shape are fundamental metrics for related research, but current in vivo measurement techniques are generally limited to the optical axis of the eye. We describe a high resolution, time domain low coherence interferometry based optometer for measuring the eye length of small animals over a wide field of view. The system is based upon a Michelson interferometer using a superluminescent diode as a source, including a sample arm and a reference arm. The sample arm is split into two paths by a polarisation beam splitter; one focuses the light on the cornea and the other focuses the light on the retina. This method has a high efficiency of detection for reflections from both surfaces. The reference arm contains a custom high speed linear motor with 25 mm stroke and equipped with a precision displacement encoder. Light reflected from the cornea and the retina is combined with the reference beam to generate low coherence interferograms. Two galvo scanners are employed to steer the light to different angles so that the eye length over a field of view of 20° × 20° can be measured. The system has an axial resolution of 6.8 μm (in air) and the motor provides accurate movement, allowing for precise and repeatable measurement of coherence peak positions. Example scans from a tree shrew are presented.
机译：随着全球近视患病率的上升，对眼睛生长调节的兴趣迅速增长。眼睛长度和眼睛形状是相关研究的基本指标，但是当前的体内测量技术通常仅限于眼睛的光轴。我们描述了一种基于高分辨率，时域低相干干涉测量技术的视力计，用于在广阔的视野内测量小动物的眼睛长度。该系统基于使用超发光二极管作为光源的迈克尔逊干涉仪，包括样品臂和参考臂。样品臂被偏振分束器分成两条路径；一个将光线聚焦在角膜上，另一个将光线聚焦在视网膜上。该方法对于检测来自两个表面的反射具有很高的效率。参考臂包含一个定制的高速线性电机，行程为25 mm，并配备了一个精密位移编码器。从角膜和视网膜反射的光与参考光束合并以生成低相干干涉图。使用两个振镜扫描器将光转向不同的角度，以便可以测量20°×20°视场上的眼睛长度。该系统的轴向分辨率为6.8μm（在空气中），电动机提供了精确的运动，从而可以精确且可重复地测量相干峰位置。给出了来自树sh的示例扫描。

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