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Nano-particle doped hydroxyapatite material evaluation using Spectroscopic Polarization Sensitive Optical Coherence Tomography

机译:光谱偏振敏感光学相干层析成像技术评估纳米粒子掺杂的羟基磷灰石材料

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摘要

Bio-ceramics such as hydroxyapatite (HAp) are widely used materials in medical applications, especially as an interface between implants and living tissues. There are many ways of creating structures from HAp like electrochemical assisted deposition, biomimetic, electrophoresis, pulsed laser deposition or sol-gel processing. Our research is based on analyzing the parameters of the sol-gel method for creating thin layers of HAp. In order to achieve this, we propose to use Optical Coherence Tomography (OCT) for non-destructive and non-invasive evaluation. Our system works in the IR spectrum range, which is helpful due to the wide range of nanocomposites being opaque in the VIS range. In order to use our method we need to measure two samples, one which is a reference HAp solution and second: a similar HAp solution with nanoparticles introduced inside. We use silver nanoparticles below 300 nm. The aim of this research is to analyze the concentration and dispersion of nanodopants in the bio-ceramic matrix. Furthermore, the quality of the HAp coating and deposition process repetition have been monitored. For this purpose the polarization sensitive OCT with additional spectroscopic analysis is being investigated. Despite the other methods, which are suitable for nanocomposite materials evaluation, the OCT with additional features seems to be one of the few which belong to the NDE/NDT group. Here we are presenting the OCT system for evaluation of the HAp with nano-particles, as well as HAp manufacturing process. A brief discussion on the usefulness of OCT for bio-ceramics materials examination is also being presented.
机译:诸如羟基磷灰石(HAp)之类的生物陶瓷是医学应用中广泛使用的材料,尤其是作为植入物与活组织之间的界面。有许多方法可以从HAp创建结构,例如电化学辅助沉积,仿生,电泳,脉冲激光沉积或溶胶-凝胶加工。我们的研究基于对溶胶-凝胶法的参数进行分析,以形成薄薄的HAp层。为了实现这一目标,我们建议使用光学相干断层扫描(OCT)进行无损和无创评估。我们的系统在IR光谱范围内工作,这是有帮助的,因为在VIS范围内,很大范围的纳米复合材料都是不透明的。为了使用我们的方法,我们需要测量两个样品,一个是参考HAp溶液,另一个是:内部装有纳米粒子的类似HAp溶液。我们使用300 nm以下的银纳米颗粒。这项研究的目的是分析生物陶瓷基质中纳米掺杂剂的浓度和分散性。此外,已经监测了HAp涂层的质量和沉积过程的重复性。为此,正在研究具有附加光谱分析的偏振敏感OCT。尽管还有其他适合纳米复合材料评估的方法,但具有附加功能的OCT似乎是属于NDE / NDT组的少数几个方法之一。在这里,我们介绍用于评估具有纳米颗粒的HAp的OCT系统以及HAp的制造工艺。还简要介绍了OCT在生物陶瓷材料检查中的作用。

著录项

  • 来源
  • 会议地点 San Francisco CA(US)
  • 作者单位

    Dept. of Metrology and Optoelectronics, Faculty of Electronics, Telecommunication and Infromatics, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233 Gdansk, Poland,Dept. of Materials and Welding Engineering, Faculty of Mechanical Engineering, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233 Gdansk, Poland;

    Dept. of Metrology and Optoelectronics, Faculty of Electronics, Telecommunication and Infromatics, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233 Gdansk, Poland;

    Mateusz Gardas GAROCIN LABS, 4 Swierkowa Str. 76-200 Slupsk, Poland;

    Dept. of Metrology and Optoelectronics, Faculty of Electronics, Telecommunication and Infromatics, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233 Gdansk, Poland,Dept. of Materials and Welding Engineering, Faculty of Mechanical Engineering, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233 Gdansk, Poland;

    Dept. of Metrology and Optoelectronics, Faculty of Electronics, Telecommunication and Infromatics, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233 Gdansk, Poland;

    Dept. of Metrology and Optoelectronics, Faculty of Electronics, Telecommunication and Infromatics, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233 Gdansk, Poland;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    HAp; sol-gel; SOCT; bio-ceramics; nanoparticles; optical coherence tomography;

    机译:HAp;溶胶凝胶SOCT;生物陶瓷纳米粒子光学相干断层扫描;

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