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首页> 外文会议>Optical Coherence tomography and coherence domain optical methods in biomedicine XX >Spectroscopic low coherence interferometry using a supercontinuum source and an ultra broadband spectrometer
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Spectroscopic low coherence interferometry using a supercontinuum source and an ultra broadband spectrometer

机译：使用超连续谱源和超宽带光谱仪的光谱低相干干涉法

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摘要

Spectroscopic optical coherence tomography (SOCT) combines the imaging capability of optical coherence tomography with spectroscopic absorption information. SOCT requires a large bandwidth combined with a broadband spectrometer, due to the processing of the measured data, which includes dividing the spectrum in spectral bands. Both, spectral and axial resolution of SOCT depend on the spectral width of each window. A supercontinuum source with its broad spectrum allows a sufficient number of windows combined with a reasonable axial resolution, which depends on the application. Here a SOCT system is used in the visible spectral range from 480 to 730 nm by combining a supercontinuum light source, a Michelson interferometer and a commercial available broadband spectrometer. This wavelength range is chosen because it covers a range of useful absorbers, including that of human proteins. The system is tested with a laser dye rhodamine B for calibration and verification. Rhodamine B has an absorption peak at around 542 nm, which resembles the absorption spectrum of several proteins in the globin group. The results show that the absorption spectrum of rhodamine B can be reconstructed with sufficient accuracy and demonstrate that varying spectroscopic information can be retrieved from different depths.
机译：光谱光学相干断层扫描（SOCT）结合了光学相干断层扫描的成像功能和光谱吸收信息。由于对测量数据的处理（包括将频谱划分为频谱带），因此SOCT需要与宽带光谱仪结合的大带宽。 SOCT的光谱分辨率和轴向分辨率均取决于每个窗口的光谱宽度。具有广泛光谱的超连续谱源可提供足够数量的窗口以及合理的轴向分辨率，具体取决于应用程序。通过组合超连续谱光源，迈克尔逊干涉仪和市售宽带光谱仪，可在480至730 nm的可见光谱范围内使用SOCT系统。选择该波长范围是因为它涵盖了一系列有用的吸收剂，包括人类蛋白质的吸收剂。用激光染料若丹明B对系统进行测试，以进行校准和验证。罗丹明B在542 nm处有一个吸收峰，类似于球蛋白基团中几种蛋白质的吸收光谱。结果表明，若丹明B的吸收光谱可以以足够的精度重建，并证明可以从不同深度检索不同的光谱信息。

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  • 会议地点 San Francisco CA(US)
  • 作者

    F. Fleischhauer; S. Caujolle; T. Feuchter; R. Rajendram; L. Leick; A. Podoleanu;

  • 作者单位

    NKT Photonics A/S, Blokken 84, 3460 Birkeroed, Denmark,University of Kent, School of physical sciences, Applied Optics Group, Ingram Building, CT2 7NZ Canterbury, United Kingdom;

    NKT Photonics A/S, Blokken 84, 3460 Birkeroed, Denmark,University of Kent, School of physical sciences, Applied Optics Group, Ingram Building, CT2 7NZ Canterbury, United Kingdom;

    NKT Photonics A/S, Blokken 84, 3460 Birkeroed, Denmark;

    Moorfields Eye Hospital, 11-43 Bath Street, Greater London EC1V 9EL, United Kingdom,University College London, Institute of Ophthalmology, Gower Street, London WC1E 6BT, United Kingdom;

    NKT Photonics A/S, Blokken 84, 3460 Birkeroed, Denmark;

    University of Kent, School of physical sciences, Applied Optics Group, Ingram Building, CT2 7NZ Canterbury, United Kingdom;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Optical coherence tomography; Spectroscopy; Absorption; Spectroscopy, visible;

    机译：光学相干断层扫描；光谱学;吸收可见光谱;

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