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Estimation of elastic parameters of ovarian tissue using phase stabilized swept source optical-coherence tomography

机译:相稳定扫描源光学相干层析成像技术估算卵巢组织的弹性参数

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摘要

We have estimated the micro-mechanical properties of ovarian tissue using phase-sensitive swept source optical coherence tomography. Ovary samples were mechanically excited by periodical vibration of an ultrasound transducer. The displacement and strain of the tissues were calculated during loading. Significant difference in strain was observed between the normal and malignant ovary groups, which indicates much softer and heterogeneous tissue structure for malignant ovaries. The initial results show that the phase sensitive swept source optical coherence elastography (OCE) can be an effective tool for characterization of stiffness and other micro-mechanical properties of normal and malignant ovarian tissue.
机译:我们已经使用相敏扫描源光学相干层析成像技术评估了卵巢组织的微机械性能。卵巢样品通过超声换能器的周期性振动而机械激发。在加载期间计算组织的位移和应变。在正常和恶性卵巢组之间观察到应变的显着差异,这表明恶性卵巢的组织结构更加柔软且异质。初步结果表明,相敏扫频光源光学相干弹性成像(OCE)可以作为表征正常和恶性卵巢组织的硬度和其他微机械特性的有效工具。

著录项

  • 来源
    《Optical Elastography and Tissue Biomechanics II》|2015年|93270D.1-93270D.6|共6页
  • 会议地点 San Francisco CA(US)
  • 作者单位

    Biomedical Engineering Department,University of Connecticut, Storrs, CT 06269;

    Electrical and Computer Engineering Department,University of Connecticut, Storrs, CT 06269;

    Electrical and Computer Engineering Department,University of Connecticut, Storrs, CT 06269;

    University of Connecticut Health Center, Division of Pathology, Farmington, CT 06030;

    Electrical and Computer Engineering Department,University of Connecticut, Storrs, CT 06269,University of Connecticut Health Center, Division of Gynecologic Oncology, Farmington, CT 06030;

    Biomedical Engineering Department,University of Connecticut, Storrs, CT 06269,Electrical and Computer Engineering Department,University of Connecticut, Storrs, CT 06269;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    phase sensitive optical coherence tomography; optical elastography; displacement; strain; ovarian tissue;

    机译:相敏光学相干断层扫描;光学弹性成像移位;应变;卵巢组织;

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