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首页> 外文会议>Optical fibers and sensors for medical diagnostics and treatment applications XVI >Manufacture of Micro Fluidic Devices by Laser Welding using Thermal Transfer Printing Techniques
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Manufacture of Micro Fluidic Devices by Laser Welding using Thermal Transfer Printing Techniques

机译：使用热转移印刷技术的激光焊接制造微流控设备

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摘要

Micro-fluidic devices are widely used today in the areas of medical diagnostics and drug research, as well as for applications within the process, electronics and chemical industry. Microliters of fluids or single cell to cell interactions can be conveniently analyzed with such devices using fluorescence imaging, phase contrast microscopy or spectroscopic techniques. Typical micro-fluidic devices consist of a thermoplastic base component with chambers and channels covered by a hermetic fluid and gas tight sealed lid component. Both components are usually from the same or similar thermoplastic material. Different mechanical, adhesive or thermal joining processes can be used to assemble base component and lid. Today, laser beam welding shows the potential to become a novel manufacturing opportunity for midsize and large scale production of micro-fluidic devices resulting in excellent processing quality by localized heat input and low thermal stress to the device during processing. For laser welding, optical absorption of the resin and laser wavelength has to be matched for proper joining. This paper will focus on a new approach to prepare micro-fluidic channels in such devices using a thermal transfer printing process, where an optical absorbing layer absorbs the laser energy. Advantages of this process will be discussed in combination with laser welding of optical transparent micro-fluidic devices.
机译：如今，微流体设备广泛用于医疗诊断和药物研究领域，以及过程，电子和化学工业中的应用。使用荧光成像，相差显微镜或光谱技术，可以使用此类设备方便地分析微升液体或单细胞间相互作用。典型的微流体装置由热塑性基础部件组成，该基础部件具有被气密的流体和气密密封盖部件覆盖的腔室和通道。两种成分通常都来自相同或相似的热塑性材料。可以使用不同的机械，粘合或热连接工艺来组装基础组件和盖子。如今，激光束焊接显示出有潜力成为中型和大规模生产微流控设备的新颖制造机会，通过局部热输入和在处理过程中对设备的低热应力，可提供出色的处理质量。对于激光焊接，必须对树脂的光学吸收和激光波长进行匹配才能正确连接。本文将重点介绍一种采用热转移印刷工艺在此类设备中制备微流体通道的新方法，其中光学吸收层吸收激光能量。将结合光学透明微流体装置的激光焊接来讨论该方法的优点。

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  • 来源
  • 会议地点 San Francisco CA(US)
  • 作者

    R. Klein; K.F. Klein; T. Tobisch; D. Thoelken; M. Belz;

  • 作者单位

    TechnoScriptum Ingeniuerbuero Rolf Klein, Am Turnplatz 2, D-64823 Gross-Umstadt, Germany,Technische Hochschule Mittelhessen - University of Applied Sciences, W.-Leuschner-Str. 13, D-61169 Friedberg, Germany;

    Technische Hochschule Mittelhessen - University of Applied Sciences, W.-Leuschner-Str. 13, D-61169 Friedberg, Germany;

    Technische Hochschule Mittelhessen - University of Applied Sciences, W.-Leuschner-Str. 13, D-61169 Friedberg, Germany;

    Technische Hochschule Mittelhessen - University of Applied Sciences, W.-Leuschner-Str. 13, D-61169 Friedberg, Germany;

    World Precision Instruments Deutschland GmbH, Saarstr. 23, D-61169 Friedberg, Germany;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Thermal transfer printing; micro-fluidic; surface coating; laser absorber; laser plastic welding;

    机译：热转移印刷；微流体表面涂层;激光吸收器激光塑料焊接;

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