Anti-Translational Research: From the Bedside Back to the Bench for Reflectance Confocal Microscopy

机译：反平移研究：从床边回到工作台进行反射共聚焦显微镜

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The reflectance confocal microscope has made translational progress in dermatology. 0.5 micrometer lateral resolution, 0.75mm field-of-view and excellent temporal resolution at ～15 frames/second serve the VivaScope well in the clinic, but it may be overlooked in basic research. This work reviews high spatiotemporal confocal microscopy and presents images acquired of various samples: zebra fish embryo where melanocytes with excellent contrast overly the spinal column, chicken embryo, where myocardium is seen moving at 15 frames/ second, calcium spikes in dendrites (fluorescence mode) just beyond the temporal resolution, and human skin where blood cells race through the artereovenous microvasculature.

机译：反射共聚焦显微镜在皮肤病学上取得了进步。 0.5微米的横向分辨率，0.75毫米的视场和约15帧/秒的出色时间分辨率在临床上很好地满足了VivaScope的要求，但在基础研究中可能会被忽略。这项工作回顾了高时空共聚焦显微镜，并提供了从各种样品获得的图像：斑马鱼胚胎，其中黑色素细胞在脊柱上具有极好的对比度，鸡胚，其中心肌以15帧/秒的速度运动，树突中的钙尖峰（荧光模式）只是时间分辨率以外，人体皮肤中的血细胞就通过动静脉微血管运动。

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《Optical methods in developmental biology II》|2014年|89530M.1-89530M.10|共10页
会议地点 San Francisco CA(US)
作者
Daniel Gareau;
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The Rockefeller University Laboratory of Investigative Dermatology 1230 York Ave, New York, NY 10065;

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1. In vivo confocal microscopy of the ocular surface: From bench to bedside [J] . VillaniE., BaudouinC., EfronN., Current Eye Research . 2014,第3期

机译：眼表的体内共聚焦显微镜：从工作台到床边
2. From the bedside to the bench and back again, with corneal confocal microscopy [J] . Investigative ophthalmology & visual science . 2014,第3期

机译：使用角膜共聚焦显微镜从床头到长凳再返回
3. In vivo confocal microscopy of the ocular surface: from bench to bedside and back again. [J] . Zhivov A, Guthoff RF, Stachs O British journal of ophthalmology . 2010,第12期

机译：眼表面的体内共聚焦显微镜检查：从工作台到床边再返回。
4. The bedside diagnostic accuracy of a novice reflectance confocal microscopy reader for skin cancer detection in vivo in real-time: understanding challenges and potential pitfalls [C] . Manu Jain, Sri Varsha Pulijal, Milind Rajadhyaksha Optical biopsy XV: Toward real-time spectroscopic imaging and diagnosis . 2017

机译：新手反射共聚焦显微镜阅读器在床边的诊断准确性，可在体内实时检测皮肤癌：了解挑战和潜在陷阱
5. Cellular pattern quantication and automatic bench-marking data-set generation on confocal microscopy images. [D] . Cui, Chi. 2010

机译：共聚焦显微镜图像上的细胞模式量化和自动基准数据集生成。
6. Reflectance Confocal Microscopy of Skin In Vivo: From Bench to Bedside [O] . Milind Rajadhyaksha, Ashfaq Marghoob, Anthony Rossi, -1

机译：体内皮肤反射共聚焦显微镜：从工作台到床边
7. In vivo confocal microscopy of the ocular surface : from bench to bedside [O] . Villani, Edoardo, Baudouin, Christophe, Efron, Nathan, 2014

机译：眼表的体内共聚焦显微镜：从工作台到床边

Anti-Translational Research: From the Bedside Back to the Bench for Reflectance Confocal Microscopy

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