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Quenching of the luminescence of nanomarkers bound to proteins by heavy metals

机译:重金属与蛋白质结合的纳米标记发光的猝灭

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The effect of heavy metal ions on the fluorescence of semiconductor ZnCdS nanoparticles in albumin solution has been studied. It is found that the fluorescence intensity of ZnCdS nanoparticles depends on the albumin concentration in the solution. Interacting with ZnCdS nanoparticles, heavy metals differently affect the fluorescence intensity of the nanoparticles. Copper ions induce fluorescence quenching, cadmium ions increase the fluorescence intensity, and zinc ions do not affect the fluorescence intensity. ZnCdS nanoparticles are the most sensitive to copper ions. Albumin enhances the effect of copper ions. The results on the influence of heavy metals on the fluorescence intensity of ZnCdS nanoparticles can be used to create a selective sensor for determination of copper ions in proteins using fluorescence quenching.
机译:研究了重金属离子对白蛋白溶液中半导体ZnCdS纳米粒子荧光的影响。发现ZnCdS纳米颗粒的荧光强度取决于溶液中白蛋白的浓度。重金属与ZnCdS纳米粒子相互作用,会不同程度地影响纳米粒子的荧光强度。铜离子诱导荧光猝灭,镉离子增加荧光强度,锌离子不影响荧光强度。 ZnCdS纳米颗粒对铜离子最敏感。白蛋白增强铜离子的作用。重金属对ZnCdS纳米粒子荧光强度的影响的结果可用于创建选择性传感器,用于使用荧光猝灭法测定蛋白质中的铜离子。

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