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3D Optical Contrast-Recovery in MR guided Diffuse Optical Spectroscopy

机译：MR引导的漫射光谱中的3D光学对比度恢复

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It is well known that diffuse optical tomography (DOT) has limited spatial resolution, and sufficient contrast recovery is limited to lesions greater than ～6 mm[l]. However, with the addition of multimodality methods that combine high spatial resolution imaging, such as MRI, it has been shown that quantification and feature recovery improves[2]. However, it is not known how well MRg-DOS will perform with characterizing small lesions in 3D. These limits need to be established in order to determine the practical limitations of optical imaging.rnThis paper investigates the contrast resolution limits of 3 dimensional MRg-DOS. Short irregular inclusions of various diameters are added to a homogeneous background. Two case studies are presented which represent these limiting situations.
机译：众所周知，漫射光学层析成像（DOT）的空间分辨率有限，并且对于大于〜6 mm的病灶，足够的对比度恢复受到限制。但是，随着增加了结合高分辨率空间成像的多模态方法（如MRI），已显示出量化和特征恢复得以改善[2]。但是，尚不知道MRg-DOS在表征3D小病变方面的表现如何。为了确定光学成像的实际限制，需要建立这些限制。rn本文研究了3D MRg-DOS的对比度分辨率限制。将各种直径的短不规则夹杂物添加到均匀背景中。提出了两个代表这些局限情况的案例研究。

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