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Oral Diseases: From Detection to Diagnostics

机译:口腔疾病:从检测到诊断

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摘要

In addition to saliva, other oral components such as gingival crevicular fluid, epithelial cells, bacteria, breath, and dental plaque have diagnostic potential. For oral diseases such as caries and periodontal disease, visual diagnosis is usually adequate, but objective diagnostic tests with predictive value are desired. Therefore, prediction models like the Cariogram have been developed that also include oral aspects such as saliva secretion, buffering capacity, and Streptococcus mutatis counts for the prediction of caries. Correlation studies on salivary components and caries have not been conclusive, but correlation studies on functional aspects, such as saliva-induced bacterial aggregation and caries, look promising. Modern proteomic techniques make it possible to study simultaneously the many salivary components involved in these functions.
机译:除唾液外,其他口腔成分(如龈沟液,上皮细胞,细菌,呼吸和牙菌斑)也具有诊断潜力。对于龋齿和牙周疾病等口腔疾病,视觉诊断通常是足够的,但需要具有预测价值的客观诊断测试。因此,已经开发出了诸如Cariogram之类的预测模型,该模型还包括诸如唾液分泌,缓冲能力和变形链球菌计数之类的口腔方面,用于预测龋齿。唾液成分和龋齿的相关性研究尚无定论,但功能方面的相关性研究,如唾液诱导的细菌聚集和龋齿,似乎很有希望。现代蛋白质组学技术可以同时研究这些功能中涉及的许多唾液成分。

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