Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid First Clinical Data

机译：牙龈沟液中活性MMP-8的快速定量椅子旁测试的初步临床数据

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In a first pilot field study 64 gingival crevicular fluid (GCF) samples were collected from patients of dental practitioners. The dentists (one orthodontist one periodontist, and one general practitioner) were asked to monitor the respective clinical status of the sites of sampling and to collect, if possible, sulcus fluid samples from healthy as well as affected sites from the same patient. The concentration of activated matrix metalloproteinase-8 (aMMP-8) in the GCF was recorded using a set of monoclonal antibodies and a novel DentoAnalyzer. From all three dental offices the distribution of the aMMP-8 values in GCF showed a congruent pattern, where healthy and periodontitis-affected inflamed sites were clearly disparate.

机译：在第一个中试研究中，从牙科医生的患者中收集了64个牙龈沟液（GCF）样品。要求牙医（一名牙齿矫正医生，一名牙周病医生和一名全科医生）监视采样部位的各自临床状况，并在可能的情况下收集健康患者以及受影响患者同一部位的龈沟液样本。使用一组单克隆抗体和新型DentoAnalyzer记录了GCF中活化基质金属蛋白酶8（aMMP-8）的浓度。在所有三个牙科诊所中，GCF中aMMP-8值的分布显示出一致的模式，其中健康和牙周炎影响的发炎部位明显不同。

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来源
《Oral-Based Diagnostics; Annals of the New York Academy of Sciences; vol.1098》|2006年|493-495|共3页
会议地点 Lake Lanier IslandsGA(US)
作者
N. PRESCHER; K. MAIER; S. K. MUNJAL; T. SORSA; C.-D. BAUERMEISTER; F. STRUCK; L. NETUSCHIL;
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作者单位

Dental Clinic, Friedrich Schiller University, Jena, Germany;

Dentognostics GmbH, Jena, Germany;

Department of Oral and Maxillofacial Diseases, Institute of Dentistry, University of Helsinki, Helsinki, Finland;

Laboratories for Oral Microbiology, Dusseldorf G;

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原文格式 PDF
正文语种 eng
中图分类诊断学;
关键词
chairside; dentoanalyzer; immunoassay; MMP8; peri-odontitis; point-of-care;

机译：椅子旁牙本质分析仪免疫测定MMP8；牙周炎;即时护理;

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专利

1. Relationship of the subgingival microbiota to a chairside test for aspartate aminotransferase in gingival crevicular fluid. [J] . Wong MY, Lu CL, Liu CM, Journal of Periodontology . 1999,第1期

机译：龈下微生物群与龈沟液中天冬氨酸转氨酶的椅旁试验的关系。
2. Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis. [J] . Mantyla P, Stenman M, Kinane DF, Journal of periodontal research . 2003,第4期

机译：龈沟液胶原酶2（MMP-8）测试棒，用于在椅旁监测牙周炎。
3. Gingival crevicular blood glucose assessment as a chairside test for diabetic patients with chronic periodontitis: A clinical study [J] . K. Suneetha, T. Rambabu Indian Journal of Endocrinology and Metabolism . 2012,第4期

机译：糖尿病慢性牙周炎患者牙龈沟血糖评估作为一项椅旁测试的临床研究
4. Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid First Clinical Data [C] . N. PRESCHER, K. MAIER, S. K. MUNJAL, Conference on Oral-Based Diagnostics . 2007

机译：在牙龈沟槽中的活性MMP-8快速定量席位试验首先临床数据
5. Association of IL-1B gene polymorphism with IL-1beta levels in gingival crevicular fluid (GCF) and bacterial profile in patients with periodontitis. [D] . Pani, Pinelopi. 2015

机译：IL-1B基因多态性与牙周炎患者龈沟液（GCF）中IL-1beta水平和细菌分布的关系。
6. Expression of β-catenin and MMP-8 in gingival crevicular fluid and gingival tissue indicates the disease severity of patients with chronic periodontitis [O] . Lilei Zhu, Yao Yao, Jian Liu, -1

机译：牙龈沟液和牙龈组织中β-catenin和MMP-8的表达表明慢性牙周炎患者的疾病严重程度
7. The Adjunctive Effect of Tenoxicam During Non-Surgical Periodontal Treatment on Clinical Parameters and Gingival Crevicular Fluid Levels of MMP-8 and TNF-α in Patients with Chronic Periodontitis – Randomized, Double-Blind Clinical Trial [O] . Özgür Özgören, Hakan Develioglu, Güliz Güncü, 2014

机译：兔慢性牙周炎患者临床参数和TNF-α临床参数和TNF-α临床参数和牙龈颈渗透液水平的辅助作用 - 随机临床试验

Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid First Clinical Data

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