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首页> 外文会议>Mechanisms of Photobiomodulation Therapy XIII >Therapeutic effect of forearm low level light treatment on blood flow, oxygenation, and oxygen consumption
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Therapeutic effect of forearm low level light treatment on blood flow, oxygenation, and oxygen consumption

机译：前臂弱光治疗对血流量，氧合和耗氧量的治疗作用

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摘要

Low level light/laser therapy (LLLT) is considered as a novel, non-invasive, and potential therapy in a variety of psychological and physical conditions, due to its effective intricate photobiomodulation. The mechanism of LLLT is that when cells are stimulated by photons, mitochondria produce a large quantity of ATP, which accelerates biochemical responses in the cell. It is of great significance to gain a clear insight into the change or interplay of various physiological parameters. In this study, we used functional near-infrared spectroscopy (fNIRS) and venous-occlusion plethysmography to measure the LLLT-induced changes in blood flow, oxygenation, and oxygen consumption in human forearms in vivo. Six healthy human participants (4 males and 2 females) were administered with 810-nm light emitted by LED array in ten minutes and blood flow, oxygenation and oxygen consumption were detected in the entire experiment. We found that LLLT induced an increase of blood flow and oxygen consumption on the treated site. Meanwhile, LLLT took a good role in promoting oxygenation of regional tissue, which was indicated by a significant increase of oxygenated hemoglobin concentration (Δ[HbO2]), a nearly invariable deoxygenated hemoglobin concentration (A[Hb]). These results not only demonstrate enormous potential of LLLT, but help to figure out mechanisms of photobiomodulation.
机译：由于其有效的复杂的光生物调节作用，低水平的光/激光疗法（LLLT）被认为是在各种心理和生理条件下的一种新颖，无创且潜在的疗法。 LLLT的机制是当光子刺激细胞时，线粒体会产生大量的ATP，从而加速细胞中的生化反应。清楚了解各种生理参数的变化或相互作用具有重要意义。在这项研究中，我们使用功能性近红外光谱（fNIRS）和静脉阻塞体积描记术来测量LLLT诱导的人体前臂在体内的血流，充氧和耗氧量的变化。在十分钟内，对六名健康的人类参与者（4名男性和2名女性）进行了LED阵列发射的810 nm光的照射，并在整个实验中检测了血流量，氧合和耗氧量。我们发现LLLT导致治疗部位的血流量和氧气消耗增加。同时，LLLT在促进局部组织的氧合作用方面起着良好的作用，其表现为氧合血红蛋白浓度（Δ[HbO2]）显着增加，而脱氧血红蛋白浓度几乎不变（A [Hb]）。这些结果不仅证明了LLLT的巨大潜力，而且有助于弄清光生物调节的机制。

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  • 来源
    《Mechanisms of Photobiomodulation Therapy XIII》|2018年|1047707.1-1047707.6|共6页
  • 会议地点 San Francisco(US)
  • 作者

    Pengbo Wang; Jiajing Sun; Lingkang Meng; Zebin Li; Ting Li;

  • 作者单位

    State Key Lab of Electronic Thin Films Integrated Devices, University of Electronic Science Technology of China, Chengdu, China;

    State Key Lab of Electronic Thin Films Integrated Devices, University of Electronic Science Technology of China, Chengdu, China;

    State Key Lab of Electronic Thin Films Integrated Devices, University of Electronic Science Technology of China, Chengdu, China;

    State Key Lab of Electronic Thin Films Integrated Devices, University of Electronic Science Technology of China, Chengdu, China;

    Biomedical Engineering Institute, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    low level light therapy (LLLT); functional near-infrared spectroscopy (fNIRS); oxygenation; blood flow; oxygen consumption;

    机译：低水平光疗（LLLT）；功能近红外光谱（fNIRS）；氧合血流（量;耗氧量;

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