首页> 外文会议>Mechanisms of Photobiomodulation Therapy XIII >LED Photochemotherapy against Staphylococcus aureus: an in vitro study
【24h】

LED Photochemotherapy against Staphylococcus aureus: an in vitro study

机译:LED针对金黄色葡萄球菌的光化学疗法:一项体外研究

获取原文
获取原文并翻译 | 示例

摘要

Bacterial resistance to antibiotics is reality and need for alternative treatments is urgent. The aim of this work was to evaluate, in vitro, the effect of LED photochemotherapy on Staphylococcus aureus (ATCC 23529) using 25 μg / mL of phenothiazine compound combined with LED light (λ632 ± 2ηm) using 12 J/cm~2 energy density. The experiments were carried out in triplicate and the samples were divided into groups: Control, Irradiated (treated only with light), Photosensitizer (treated only in the presence of the dye), LED-Photochemotherapy (treatment with light associated with dye). Counts of the colony forming units and the data obtained were statistically analyzed (ANOVA, Tukey's test, p<0.05). The present study demonstrated that the efficacy of LED-Photochemotherapy as the use of 25 ng/mL × 12 J/cm~2 caused 91.57 % of inhibition of bacterial growth. It is concluded that using energy density of 12 J/cm~2 associated to 25 μg/mL caused high in vitro inhibition of S. aureus.
机译:细菌对抗生素的耐药性已成为现实,迫切需要替代疗法。这项工作的目的是在体外评估采用25μg/ mL吩噻嗪化合物并结合12J / cm〜2能量密度的LED光(λ632±2ηm)的LED光化学疗法对金黄色葡萄球菌(ATCC 23529)的影响。实验一式三份进行,并将样品分成组:对照,辐照(仅用光处理),光敏剂(仅在染料存在下处理),LED光化学疗法(用与染料相关的光处理)。统计分析菌落形成单位的数目和获得的数据(ANOVA,Tukey检验,p <0.05)。本研究表明,采用25 ng / mL×12 J / cm〜2的LED光化学疗法可产生91.57%的细菌生长抑制作用。结论是,使用与25μg/ mL相关的12 J / cm〜2的能量密度会导致对金黄色葡萄球菌的高度体外抑制。

著录项

  • 来源
    《Mechanisms of Photobiomodulation Therapy XIII》|2018年|104770S.1-104770S.5|共5页
  • 会议地点 San Francisco(US)
  • 作者单位

    Center of Biophotonics, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil, 40110-150;

    Center of Biophotonics, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil, 40110-150,Department of Biology, Estate University of Feira de Santana, Feira de Santana, BA, Brazil, 44036-900;

    Center of Biophotonics, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil, 40110-150;

    Center of Biophotonics, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil, 40110-150;

    Center of Biophotonics, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil, 40110-150,National Institute Basic Optics and Applied to Life Science, Sao Carlos, SP, Brazil, 13560-970;

    Center of Biophotonics, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil, 40110-150;

    Center of Biophotonics, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil, 40110-150,National Institute Basic Optics and Applied to Life Science, Sao Carlos, SP, Brazil, 13560-970;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    AmPDT; Bacteria; Light Emitting Diode; Methylene Blue; Toluidine blue.;

    机译:AmPDT;菌;发光二极管;亚甲蓝;甲苯胺蓝。;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号