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首页> 外文会议>Mechanisms of Photobiomodulation Therapy XIV >In vivo quantification of nitric oxide (NO) release from intact human skin following exposure to photobiomodulation wavelengths in the visible and near-infrared spectrum
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In vivo quantification of nitric oxide (NO) release from intact human skin following exposure to photobiomodulation wavelengths in the visible and near-infrared spectrum

机译：暴露于可见光和近红外光谱中的光生物调节波长后，从完整人体皮肤中释放的一氧化氮（NO）的体内定量

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摘要

Human skin contains photolabile nitric oxide (NO) derivatives which decompose after UVA irradiation and releasevasoactive NO. However, aside from blue light, barely nothing has been reported about the effects of red and NIRwavelengths. We decided to investigate if photobiomodulation, using visible to NIR light, would increase the release ofNO in the skin. A custom-built airtight sleeve which envelopes the forearm of a subject was used to measure the NOemanating from the skin under photobiomodulation conditions and quantified by chemiluminescence detection. Distinctdifferences in measured NO levels were observed between the non-irradiated condition and PBM conditions.
机译：人体皮肤含有光不稳定的一氧化氮（NO）衍生物，这些衍生物会在UVA照射后分解并释放\血管活性的NO。但是，除了蓝光之外，几乎没有关于红色和NIR \ r \ n波长的影响的报道。我们决定研究使用近红外可见光进行的光生物调节是否会增加皮肤中\ r \ nNO的释放。使用定制的密封对象的前臂的气密性套筒来测量在光生物调节条件下从皮肤发出的NO \ r \ r \ n，并通过化学发光检测进行定量。在未辐照条件和PBM条件之间观察到NO含量的差异。

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  • 来源
    《Mechanisms of Photobiomodulation Therapy XIV》|2019年|108610G.1-108610G.7|共7页
  • 会议地点 1605-7422;2410-9045
  • 作者

    Augustin C. Barolet; Gregory Cormack; Gabriel Lachance; Mathieu Auclair; Daniel Barolet;

  • 作者单位

    McGill University, 1001 Décarie Blvd, Montreal, Qc, Canada, H4A 3J1 RoseLab Skin Optics Research Laboratory, 3333 100th Ave, Laval, Qc, Canada, H7T 0G3;

    RoseLab Skin Optics Research Laboratory, 3333 100th Ave, Laval, Qc, Canada, H7T 0G3;

    RoseLab Skin Optics Research Laboratory, 3333 100th Ave, Laval, Qc, Canada, H7T 0G3;

    RoseLab Skin Optics Research Laboratory, 3333 100th Ave, Laval, Qc, Canada, H7T 0G3;

    McGill University, 1001 Décarie Blvd, Montreal, Qc, Canada, H4A 3J1 RoseLab Skin Optics Research Laboratory, 3333 100th Ave, Laval, Qc, Canada, H7T 0G3;

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