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Present status of photodynamic procedures in urology

机译:光动力程序在泌尿外科的现状

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Abstract: Since 1976, photodynamic therapy (PDT) has been used for the treatment of different stages of urothelial bladder tumors. First applications were based on the irradiation of single exophytic tumors using bare fibers for laser irradiation (630 mm) or bright white light generated e.g. from a mercury arc lamp. Clinical results of several centers demonstrated the possibility of destroying single superficially growing tumors. A new approach to the treatment of multifocal growing tumors, including the endoscopically often undetectable carcinoma in situ, was provided by the development of treatment modalities allowing for whole bladder wall irradiation. Photodynamic diagnosis (PDD) is a novel procedure for detecting flat precancerous and malignant lesions undetectable by endoscopy alone on the basis of laser-induced fluorescence. !21
机译:摘要:自1976年以来,光动力疗法(PDT)已用于治疗尿路上皮膀胱肿瘤的不同阶段。最初的应用是基于使用裸露的纤维对激光进行单个辐照性肿瘤的辐照(630 mm),或者产生明亮的白光,例如光散射。来自水银弧光灯。多个中心的临床结果表明,有可能破坏单个表面生长的肿瘤。通过开发允许整个膀胱壁照射的治疗方式,提供了一种新的治疗多灶性生长瘤的方法,包括内窥镜检查通常无法检测到的原位癌。光动力诊断(PDD)是一种新颖的程序,用于根据激光诱导的荧光来检测仅靠内窥镜检查无法检测到的扁平癌前和恶性病变。 !21

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