• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Photonic therapeutics and diagnostics X >Rapid Infrared Laser Sealing and Cutting of Porcine Renal Vessels, Ex Vivo
【24h】

Rapid Infrared Laser Sealing and Cutting of Porcine Renal Vessels, Ex Vivo

机译：猪肾血管的快速红外激光密封和切割，体外

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Suture ligation with subsequent cutting of blood vessels to maintain hemostasis during surgery is time consuming and skill intensive. Energy-based, electrosurgical and ultrasonic devices are often used to replace sutures and mechanical clips to provide rapid hemostasis, and decrease surgical time. Some of these devices may create undesirably large collateral zones of thermal damage and tissue necrosis, or require separate mechanical blades for cutting. Infrared lasers are currently being explored as alternative energy sources for vessel sealing applications. In a previous study, a 1470-nm laser was used to seal vessels of 1-6 mm in diameter in 5 s, yielding burst pressures of ～ 500 mmHg. The purpose of this study was to provide faster sealing, incorporate transection of the sealed vessels, and increase the burst pressure. A 110-Watt, 1470-nm laser beam was transmitted through a fiber and beam shaping optics, producing a linear beam 3.0 mm by 9.5 mm for sealing, and 1.1 mm by 9.6 mm for cutting (FWHM). A two-step process sealed then transected ex vivo porcine renal vessels (1-8.5 mm diameter) in a bench top setup. Seal and cut times were 1.0 s each. A standard burst pressure system measured resulting seal strength, and gross and histologic thermal damage measurements were also recorded. All blood vessels tested (n = 30) were sealed and cut, with total irradiation times of 2.0 s, mean burst pressures ＞ 1000 mmHg (compared to normal systolic blood pressure of 120 mmHg), and combined seal/collateral thermal coagulation zones of 2-3 mm. The results of this study demonstrated that an optical-based system is capable of precisely sealing and cutting a wide range of porcine renal vessel sizes, and with further development, may provide an alternative to radiofrequency and ultrasound-based vessel sealing devices.
机译：缝合结扎线并随后切断血管以在手术期间维持止血是耗时且技能密集的。基于能量的电外科和超声设备通常用于代替缝合线和机械夹，以提供快速止血，并减少手术时间。这些设备中的一些可能会产生不希望的较大的热损伤和组织坏死的附带区域，或者需要单独的机械刀片进行切割。目前正在探索将红外激光用作容器密封应用的替代能源。在先前的研究中，使用1470-nm激光在5 s内密封直径1-6 mm的血管，产生的爆破压力约为500 mmHg。这项研究的目的是提供更快的密封，合并密封血管的横切，并增加破裂压力。 110瓦，1470 nm的激光束通过光纤和光束成形光学器件传输，产生3.0 mm x 9.5 mm的线性光束用于密封，而1.1 mm x 9.6 mm的线性光束用于切割（FWHM）。分两步密封，然后在台式装置中横穿离体猪肾血管（直径为1-8.5 mm）。密封和切割时间均为1.0 s。标准爆破压力系统测量了所得密封强度，并且还记录了总体和组织学热损伤测量值。密封并切断所有测试的血管（n = 30），总照射时间为2.0 s，平均破裂压力＞ 1000 mmHg（与正常收缩压为120 mmHg相比），并且密封/并行热凝结区域为2个-3毫米这项研究的结果表明，基于光学的系统能够精确地密封和切割各种尺寸的猪肾血管，并且随着进一步的发展，它可以为基于射频和超声的血管密封装置提供替代方案。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号