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首页> 外文会议>Photonic therapeutics and diagnostics X >Characterization of a 50-μm-Core Optical Fiber for Potential use in Thulium Fiber Laser Lithotripsy
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Characterization of a 50-μm-Core Optical Fiber for Potential use in Thulium Fiber Laser Lithotripsy

机译：潜在用于in光纤激光碎石术的50μm芯光纤的特性

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Our laboratory is currently studying the Thulium fiber laser (TFL) as a potential alternative laser lithotripter to the standard clinical Holmium:YAG laser. We have previously demonstrated efficient coupling of TFL energy into fibers as small as 100-μm-core-diameter without damage to the proximal end. Although smaller fibers have greater tendency to degrade at the distal tip during lithotripsy, fiber diameters (≤ 200 μm) have been shown to increase saline irrigation rates through the working channel of a flexible ureteroscope, maximize ureteroscope deflection, and reduce stone retropulsion during laser lithotripsy. In this study, a 50-μm-core-diameter, 85-μm-outer-diameter fiber is characterized for TFL ablation of human calcium oxalate monohydrate urinary stones, ex vivo. The stone ablation rate was measured to be 70 ± 22 μg/s for 35-mJ-pulse-energy, 500-μs-pulse-duration, and 50-Hz-pulse-rate. The ureteroscope working channel flow rate including the 50-um fiber decreased by only 10% with no impairment of ureteroscope deflection. The fiber delivered up to 15.4 ± 5.9 W under extreme bending (5-mm-radius) conditions. Stone retropulsion and fiber burn-back averaged 201 ± 336 and 3000 ± 2600 μm, respectively, after 2 minutes. With further development, Thulium fiber laser lithotripsy using ultra-small, 50-μm-core fibers may introduce new integration and miniaturization possibilities and potentially provide an alternative to conventional HolmiunrYAG laser lithotripsy using larger fibers.
机译：我们的实验室目前正在研究ul光纤激光器（TFL），它可以替代标准临床clinical：YAG激光器。我们之前已经证明了TFL能量可以有效地耦合到直径100μm的小直径纤维中，而不会损坏近端。尽管较小的纤维在碎石术中在远端尖端具有更大的降解趋势，但纤维直径（≤200μm）已显示出通过柔性输尿管镜的工作通道提高盐水冲洗速率，最大化输尿管镜偏转并减少激光碎石术中的结石后退。在这项研究中，以50μm核心直径，85μm外径的纤维为特征，用于离体对人类草酸钙一水合尿路结石进行TFL消融。对于35 mJ脉冲能量，500μs脉冲持续时间和50 Hz脉冲频率，测得的结石消融速率为70±22μg/ s。包括50微米光纤在内的输尿管镜工作通道流速仅降低了10％，而不会损害输尿管镜的偏转。在极端弯曲（半径为5毫米）的条件下，光纤的输出功率高达15.4±5.9W。 2分钟后，碎石后退和纤维回燃平均分别为201±336和3000±2600μm。随着进一步的发展，使用超小，50μm纤芯光纤的Th光纤激光碎石术可能会带来新的集成和小型化可能性，并有可能为使用较大光纤的常规HolmiunrYAG激光碎石术提供替代方案。

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