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Self optical motion-tracking for endoscopic Optical coherence tomography probe using micro-beamsplitter probe

机译：内窥镜光学相干断层扫描探头的自光学运动跟踪，采用微分束器探头

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摘要

Long range optical coherence tomography (OCT), with its high speed, high resolution, non-ionized properties and cross-sectional imaging capability, is suitable for upper airway lumen imaging. To render 2D OCT datasets to true 3D anatomy, additional tools are usually applied, such as X-ray guidance or a magnetic sensor. X-ray increases ionizing radiation. A magnetic sensor either increases probe size or requires an additional pull-back of the tracking sensor through the body cavity. In order to overcome these limitations, we present a novel tracking method using a 1.5 mm×1.5mm, 90/10-ratio micro-beamsplitter: 10% light through the beam-splitter is used for motion tracking and 90% light is used for regular OCT imaging and motion tracking. Two signals corresponding to these two split-beams that pass through different optical path length delays are obtained by the detector simultaneously. Using the two split beams' returned signals from the same marker line, the 2D inclination angle of each step is computed. By calculating the 2D inclination angle of each step and then connecting the translational displacements of each step, we can obtain the 2D motion trajectory of the probe. With two marker lines on the probe sheath, 3D inclination angles can be determined and then used for 3D trajectory reconstruction. We tested the accuracy of trajectory reconstruction using the probe and demonstrated the feasibility of the design for structure reconstruction of a biological sample using a porcine trachea specimen. This optical-tracking probe has the potential to be made as small as an outer diameter of 1.0mm, which is ideal for upper airway imaging.
机译：远程光学相干断层扫描（OCT）具有高速，高分辨率，非电离特性和横截面成像能力，适用于上呼吸道内腔成像。为了将2D OCT数据集渲染为真实的3D解剖结构，通常会应用其他工具，例如X射线引导或磁传感器。 X射线会增加电离辐射。磁传感器要么增加探头的尺寸，要么需要通过体腔额外拉回跟踪传感器。为了克服这些限制，我们提出了一种使用1.5 mm×1.5mm，比率为90/10的微分束器的新颖跟踪方法：通过分束器的10％的光用于运动跟踪，而将90％的光用于定期进行OCT成像和运动跟踪。检测器同时获得对应于通过不同光程长度延迟的这两个分离光束的两个信号。使用来自同一标记线的两个分离光束返回的信号，计算每个台阶的2D倾斜角。通过计算每个台阶的2D倾斜角度，然后连接每个台阶的平移位移，我们可以获得探头的2D运动轨迹。通过在探头护套上的两条标记线，可以确定3D倾斜角度，然后将其用于3D轨迹重建。我们使用探针测试了轨迹重建的准确性，并证明了使用猪气管标本对生物样品进行结构重建的设计可行性。这种光学跟踪探头的制造潜力可小至1.0mm的外径，非常适合上呼吸道成像。

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  • 来源
    《Photonic therapeutics and diagnostics X》|2014年|892622.1-892622.7|共7页
  • 会议地点 San Francisco CA(US)
  • 作者

    Jiawen Li; Jun Zhang; Lidek Chou; Alex Wang; Joseph Jing; Zhongping Chen;

  • 作者单位

    Department of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617;

    Department of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617;

    Department of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617;

    Department of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617;

    Department of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617;

    Department of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617;

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