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Optical nerve stimulation for a vestibular prosthesis

机译：视神经刺激前庭假体

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Infrared Nerve Stimulation (INS) offers several advantages over electrical stimulation, including more precise spatial selectivity and improved surgical access. In this study, INS and electrical stimulation were compared in their ability to activate the vestibular branch of the VIIIth nerve, as a potential way to treat balance disorders. The superior and lateral canals of the vestibular system of Guinea pigs were identified and approached with the aid of precise 3-D reconstructions. A monopolar platinum stimulating electrode was positioned near the ampullae of the canals, and biphasic current pulses were used to stimulate vestibular evoked potentials and eye movements. Thresholds and input/output functions were measured for various stimulus conditions. A short pulsed diode laser (Capella, Lockheed Martin-Aculight, Inc., Bothell WA) was placed in the same anatomical position and various stimulus conditions were evaluated in their ability to evoke similar potentials and eye movements.
机译：红外神经刺激（INS）与电刺激相比具有多个优点，包括更精确的空间选择性和改善的手术通道。在这项研究中，比较了INS和电刺激激活VIII神经前庭分支的能力，将其作为治疗平衡障碍的潜在方法。豚鼠的前庭系统的上，外侧管已被确定，并借助精确的3D重建而接近。将单极铂刺激电极置于运河壶腹附近，并使用双相电流脉冲刺激前庭诱发电位和眼球运动。测量各种刺激条件的阈值和输入/输出功能。将短脉冲二极管激光器（Capella，Lockheed Martin-Aculight，Inc.，Bothell）放置在相同的解剖位置，并评估了各种刺激条件引起其类似电位和眼球运动的能力。

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