Photoacoustic Tomography and Molecular Fluorescence Imaging: Dual Modality Imaging of Small Animal Brains In Vivo

机译：光声层析成像和分子荧光成像：小动物体内的双模态成像。

获取原文

获取原文并翻译 | 示例

页面导航

摘要
著录项
相似文献
相关主题

摘要

We present a dual modality imaging technique by combining photoacoustic tomography (PAT) and near-infrared (NIR) fluorescence imaging for the study of animal model tumors. PAT provides high-resolution structural images of tumor angiogenesis, and fluorescence imaging offers high sensitivity to molecular probes for tumor detection. Coregistration of the PAT and fluorescence images was performed on nude mice with M21 human melanoma cell lines with αvβ3 integrin expression. An integrin αvβ3-targeted peptide-ICG conjugated NIR fluorescent contrast agent was used as the molecular probe for tumor detection. PAT was employed to noninvasively image the brain structures and the angiogenesis associated with tumors in nude mice. Coregistration of the PAT and fluorescence images was used in this study to visualize tumor location, angiogenesis, and brain structure simultaneously.

机译：我们提出了一种通过结合光声层析成像（PAT）和近红外（NIR）荧光成像技术来研究动物模型肿瘤的双模态成像技术。 PAT可提供肿瘤血管生成的高分辨率结构图像，而荧光成像可对用于肿瘤检测的分子探针提供高灵敏度。在具有αvβ3整合素表达的M21人黑素瘤细胞系的裸鼠上进行PAT和荧光图像的配准。使用整合素αvβ3靶向肽-ICG偶联的NIR荧光造影剂作为检测肿瘤的分子探针。 PAT被用于无创成像裸鼠的大脑结构和与肿瘤相关的血管生成。 PAT的配向和荧光图像用于这项研究，以同时可视化肿瘤的位置，血管生成和脑结构。

著录项

来源
《Photons Plus Ultrasound: Imaging and Sensing 2005; Progress in Biomedical Optics and Imaging; vol.6, no.12》|2005年|P.107-110|共4页
会议地点 San JoseCA(US)
作者
Xueyi Xie; Jung-Taek Oh; Meng-Lin Li; Geng Ku; Xueding Wang; Shi Ke; Chun Li; Sergiu Similache; George Stoica; Lihong V. Wang;
展开▼
作者单位

Optical Imaging Laboratory, Department of Biomedical Engineering, Texas AM University, College Station, TX;

展开▼
会议组织
原文格式 PDF
正文语种 eng
中图分类光、激光生物医学;
关键词
photoacoustic tomography; fluorescent imaging; molecular imaging; contrast agent;

机译：光声层析成像；荧光成像；分子成像；造影剂;

相似文献

外文文献
中文文献
专利

1. Development of a Squaraine-Based Molecular Probe for Dual-Modal in Vivo Fluorescence and Photoacoustic Imaging [J] . Yong Dae Park, Jam-Eon Park, Hyeon Sik Kim, Bioconjugate Chemistry . 2020,第11期

机译：体内荧光和光声成像的双模型分子探针的研制
2. Sentinel Lymph Nodes and Lymphatic Vessels: Noninvasive Dual-Modality in Vivo Mapping by Using Indocyanine Green in Rats—Volumetricn Spectroscopic Photoacoustic Imaging and Planar Fluorescence Imaging [J] . Chulhong Kim PhD, Kwang Hyun Song PhD, Feng Gao PhD and, Radiology . 2010,第2期

机译：前哨淋巴结和淋巴管：通过使用吲哚菁绿在大鼠体内映射的非侵入性双模式—伏尔坦光谱光声成像和平面荧光成像。
3. Sentinel lymph nodes and lymphatic vessels: noninvasive dual-modality in vivo mapping by using indocyanine green in rats--volumetric spectroscopic photoacoustic imaging and planar fluorescence imaging. [J] . Kim C, Song KH, Gao F, Radiology . 2010,第2期

机译：前哨淋巴结和淋巴管：使用吲哚菁绿在大鼠体内进行的无创双模体内测绘-体积光谱光声成像和平面荧光成像。
4. Photoacoustic Tomography and Molecular Fluorescence Imaging: Dual Modality Imaging of Small Animal Brains In Vivo [C] . Xueyi Xie, Jung-Taek Oh, Meng-Lin Li, Society of Photo-Optical Instrumentation Engineers (SPIE);SPIE Proceedings . 2005

机译：光声层析成像和分子荧光成像：小动物体内的双模态成像。
5. Dual modality optical coherence tomography and multispectral fluorescence imaging for ovarian cancer detection. [D] . Tate, Tyler Houston. 2017

机译：用于卵巢癌检测的双模式光学相干断层扫描和多光谱荧光成像。
6. In vivo molecular imaging of colorectal cancer using quantum dots targeted to vascular endothelial growth factor receptor 2 and optical coherence tomography/laser-induced fluorescence dual-modality imaging [O] . Jordan L. Carbary-Ganz, Weston A. Welge, Jennifer K. Barton, 2015

机译：大肠癌的体内分子成像使用靶向血管内皮生长因子受体2的量子点和光学相干断层扫描/激光诱导的荧光双峰成像
7. In vivomolecular imaging of colorectal cancer using quantum dots targeted to vascular endothelial growth factor receptor 2 and optical coherence tomography/laser-induced fluorescence dual-modality imaging [O] . Jordan L. Carbary-Ganz, Weston A. Welge, Jennifer K. Barton, 2015

机译：使用靶向血管内皮生长因子受体2和光学相干断层扫描/激光诱导的荧光双重模拟成像的量子点的传染性癌症成像

Photoacoustic Tomography and Molecular Fluorescence Imaging: Dual Modality Imaging of Small Animal Brains In Vivo

摘要

著录项

相似文献

相关主题

期刊订阅