Abstract: In addition to the laser, microwave or other energy sources, interstitial thermotherapy with radio-frequency current (RFITT) in bipolar technique has already been shown in vitro to be a safe and economical alternative energy source with a comparable operating performance. The bipolar technique is, from the technical point of view, completely without risk whereas with monopolar devices, where a neutral electrode has to be applied, an uncontrolled current flow passes through the patient's body. The therapeutical application efficiency of these bipolar RF-needle applicators was evaluated using newly designed high performance flushed and cooled probes (qq 3 mm). These can be used to create large coagulation volumes in tissue such as for the palliative treatment of liver metastases or the therapy of the benign prostate hyperplasia. As a result, the achievable lesion size resulting from these flushed and internally cooled RF- probes could be increased by a factor of three compared to a standard bipolar probe. With these bipolar power RF- applicators, coagulation dimensions of 5 cm length and 4 cm diameter with a power input of 40 watt could be achieved within 20 minutes. No carbonization and electrode tissue adherence was found. Investigations in vitro with adapted RFITT-probes using paramagnetic materials such as titanium alloys and high performance plastic have shown that monitoring under MRI (Siemens Magnetom, 1.5 Tesla), allows visualization of the development of the spatial temperature distribution in tissue using an intermittent diagnostic and therapeutical application. This does not lead to a loss in performance compared to continuous application. A ratio of 1:4 (15 s Thermo Flash MRI, 60 s RF-energy) has shown to be feasible.!5
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机译：摘要：除激光，微波或其他能源外，双极技术中的射频电流间隙热疗法（RFITT）已在体外被证明是一种安全经济的替代能源，具有可比的工作性能。从技术角度来看，双极技术完全没有危险，而对于单极设备，必须使用中性电极，不受控制的电流会流经患者的身体。使用新设计的高性能冲洗和冷却探头（qq 3 mm）评估了这些双极RF针头施加器的治疗应用效率。这些可用于在组织中产生大量凝血，例如用于肝转移的姑息治疗或良性前列腺增生的治疗。结果，与标准的双极探头相比，这些冲洗和内部冷却的RF探头导致的可达到的病变大小可以增加三倍。使用这些双极功率射频施加器，可以在20分钟内达到5厘米长和4厘米直径的凝结尺寸，输入功率为40瓦特。没有发现碳化和电极组织粘附。使用顺磁性材料（例如钛合金和高性能塑料）对改良的RFITT探针进行的体外研究表明，在MRI（Siemens Magnetom，1.5特斯拉）下进行的MRI监测可以通过间歇性诊断和观察来观察组织中空间温度分布的变化。治疗应用。与连续应用相比，这不会导致性能损失。 1：4的比率（15 s Thermo Flash MRI，60 s RF能量）是可行的！5
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