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首页> 外文会议>Polysaccharide materials: Performance by design >Cellulose composites prepared using ionic liquids (ILs) - Blood Compatibility to Batteries
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Cellulose composites prepared using ionic liquids (ILs) - Blood Compatibility to Batteries

机译：使用离子液体（IL）制备的纤维素复合材料-血液与电池的相容性

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The fabrication of cellulose composites using ILs has been extensively studied. A variety of novel cellulose based materials prepared by dissolving cellulose in ILs have been described. They have promise in medical applications in the forms of biofilms, biofibers, templates or foldable energy storage devices. The use of these biomaterials for pharmaceutical applications should be considered only if these cellulose composites are safe for patients. Biocompatibility and blood compatibility, the relevant safety issues for patients, are very important in biomedical engineering since the lack of biocompatibility inevitably results in device failure. Heparin-cellulose based biomaterials show excellent blood compatibility and these might be useful in various applications for extracorporeal and implantable medical devices. The properties of ILs make these important novel solvent systems for cellulose-based biomaterials. Many ILs have been synthesized to have specific desirable physical and chemical properties, such as affinity for glycosaminoglycans, viscosity, melting point, and/or electrochemical properties that are tunable by varying the structure of their cation and anion. The use of ILs to dissolve cellulose is very attractive because cellulose is generally not easily dissolved and is of great utility in energy storage devices. We conclude that cellulose and heparin-cellulose composites prepared using ILs will provide further opportunities to develop biomaterial systems useful in a wide variety of biomedical devices.
机译：已经广泛研究了使用IL制备纤维素复合材料的方法。已经描述了通过将纤维素溶解在IL中制备的多种新颖的基于纤维素的材料。它们以生物膜，生物纤维，模板或可折叠能量存储设备的形式在医学应用中具有前景。仅当这些纤维素复合材料对患者安全时，才应考虑将这些生物材料用于药物应用。生物相容性和血液相容性是患者的相关安全问题，在生物医学工程中非常重要，因为缺乏生物相容性不可避免地会导致设备故障。肝素纤维素基生物材料显示出出色的血液相容性，在体外和可植入医疗设备的各种应用中可能有用。 IL的特性使这些重要的新型溶剂系统成为了基于纤维素的生物材料。已经合成了许多具有特定的理想物理和化学性质的IL，例如对糖胺聚糖的亲和力，粘度，熔点和/或电化学性质，这些性质可通过改变其阳离子和阴离子的结构来调节。使用IL溶解纤维素非常吸引人，因为纤维素通常不容易溶解，并且在能量存储设备中很有用。我们得出的结论是，使用IL制备的纤维素和肝素-纤维素复合材料将为开发可用于多种生物医学设备的生物材料系统提供进一步的机会。

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  • 会议地点 Chicago IL(US)
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    Tae-Joon Park; rnSaravanababu Murugesan; rnRobert J. Linhardt;

  • 作者单位

    Department of Chemical and Biological Engineering Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute, Biotech Center 4005, 110 8th Street, Troy, NY 12180-3590, USA;

    rnDepartment of Chemical and Biological Engineering Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute, Biotech Center 4005, 110 8th Street, Troy, NY 12180-3590, USA Development Engineering, Process Research and Development, Bristol-Myers Squibb, New Brunswick, NJ 08903;

    rnDepartment of Chemical and Biological Engineering Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute, Biotech Center 4005, 110 8th Street, Troy, NY 12180-3590, USA Chemistry and Chemical Biology Center for Biotechnology and Interdisciplinary Studies Re;

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  • 正文语种 eng
  • 中图分类 有机质材料;
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