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首页> 外文会议>Proceedings of the Conference of Global Chinese Scholars on Hydrodynamics(CCSH'06) >NUMERICAL SIMULATION OF PULSATILE BLOOD FLOW THROUGH ASYMMETRIC ARTERIAL STENOSES UNDER EECP
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NUMERICAL SIMULATION OF PULSATILE BLOOD FLOW THROUGH ASYMMETRIC ARTERIAL STENOSES UNDER EECP

机译：EECP下脉动不对称动脉血流的数值模拟

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摘要

In this paper, a three-dimensional model of pulsatile blood flow througth a vessel with an asymmetric stenosis is developed to numerically study the hemodynamics circumstance under EECP (Enhanced External Counter Pulsation). The governing equations are the usual Navier-Stokes equations for unsteady elliptic flows, and are numerically solved by using finite volume method. The numerical computing is based on the animal experiment. The blood flow rate curves in a cadiac cycle pre-EECP and post-EECP are detected in a pig's carotid respectively, the counterpulsation pressure is 0.03MPa. The blood flow rate curves are transformed to blood velocity distributions along the arterial diameter by using the Womersley arithmetic. And the Womersley velocity profiles are used as inflow boundary conditions to simulate the whole hemodynamics circumstance inside the 3-dimensional artery model. The computational results show that when EECP is applied, the blood flow rate and the wall shear stress level of the artery are increased in a cadiac cycle, as well as the pulsatile character of blood flow and wall shear stress. Which are possibly the hemodynamic actors that lead to the improving of the endothelial function which is thought to be straightly relating to the atherosclerosis.
机译：本文建立了一个通过不对称狭窄血管的脉动血流的三维模型，以对EECP（增强的外部反搏）下的血液动力学情况进行数值研究。控制方程是用于非定常椭圆形流动的常用Navier-Stokes方程，并使用有限体积法进行了数值求解。数值计算基于动物实验。在猪的颈动脉中，分别检测出在EECP前和EECP后的循环周期中的血流量曲线，反搏压力为0.03MPa。使用Womersley算法将血流速率曲线转换为沿动脉直径的血流速度分布。 Womersley速度分布用作流入边界条件，以模拟3维动脉模型内部的整个血液动力学情况。计算结果表明，当应用EECP时，动脉的血液流速和壁切应力水平在一个循环中增加，并且血流和壁切应力的脉动特征也增加。可能是导致内皮功能改善的血液动力学因素，据认为这与动脉粥样硬化直接相关。

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