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首页> 外文会议>Proceedings of Life in space for life on earth >COMPARISON OF OCULAR OUTCOMES ACROSS TWO 14-DAY BED REST PLATFORMS
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COMPARISON OF OCULAR OUTCOMES ACROSS TWO 14-DAY BED REST PLATFORMS

机译：两种14天床位休息平台的眼外观察结果比较

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摘要

One possible mechanism for visual changesrnreported in astronauts may involve microgravityrninduced cephalad fluid shifts that lead to elevatedrnretrobulbar cerebrospinal fluid pressure. Because headdownrntilt (HDT) bed rest induces cephalad fluid shifts,rnvision monitoring was implemented for NASA bed restrncampaigns. Subjects selected for these campaigns werernhealthy adults (14 males and 5 females). In onerncampaign, subjects maintained a horizontal (0°) positionrnwhile in bed and were exercised six days per week. Inrnthe other campaign, subjects were placed at 6° HDTrnwhile in bed and did not engage in exercise. Measuresrncommon to both studies included intraocular pressurernand retinal measures derived from optical coherencerntomography. There were no significant differencesrnbetween subject groups for pre- and post bed restrntesting. These preliminary results suggest that exerciserncombined with horizontal bed rest as compared to 6°rnHDT bed rest did not produce differences in the ocularrnresponse of these subjects. Further investigation isrnneeded to examine both the acute response and longrnterm adaptation of structural and functional ocularrnparameters in the bed rest platform.
机译：宇航员报告的视觉变化的一种可能机制可能涉及微重力引起的头颅液移位，从而导致视网膜小球脑脊液压力升高。由于头枕倾斜（HDT）卧床会引起头颅积液移位，因此对NASA卧床运动进行了视觉监控。选择参加这些运动的受试者是健康成人（14名男性和5名女性）。在运动训练中，受试者躺在床上时保持水平（0°）位置，每周锻炼六天。在其他运动中，受试者在卧床时处于6°HDTrn水平，不进行运动。两项研究的共同措施包括眼内压和源自光学相干断层扫描的视网膜测量。睡前和睡后重新测试的受试者组之间没有显着差异。这些初步结果表明，与6°HDT卧床休息相结合的运动与卧式卧床休息不会在这些受试者的眼反应中产生差异。需要进一步的研究以检查卧床平台中结构和功能性眼参数的急性反应和长期适应性。

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  • 作者

    Ronita L. Cromwell; Susana B. Zanello; Patrice O. Yarbough; Giovanni Taibbi; Gianmarco Vizzeri;

  • 作者单位

    Universities Space Research Association, 3600 Bay Area Blvd., Houston, Texas, 77058 (USA), Email:ronita.l.cromwell@nasa.gov;

    Universities Space Research Association, 3600 Bay Area Blvd., Houston, Texas, 77058 (USA), Email:susana.b.zanello@nasa.gov;

    Universities Space Research Association, 3600 Bay Area Blvd., Houston, Texas, 77058 (USA), Email:patrice.o.yarbough@nasa.gov;

    University of Texas Medical Branch, 301 University Blvd., Galveston, Texas, 77555 (USA),Email:givizzer@utmb.edu;

    University of Texas Medical Branch, 301 University Blvd., Galveston, Texas, 77555 (USA),Email:gitaibbi@utmb.edu;

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