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首页> 外文会议>Proceedings of the second international conference on advanced textile materials amp; manufacturing technology. >Fabrication and Characterization of Mesoporous Calcium Silicate/silk Fibroin Composite Films
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Fabrication and Characterization of Mesoporous Calcium Silicate/silk Fibroin Composite Films

机译：介孔硅酸钙/丝素蛋白复合膜的制备与表征

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A well-defined mesoporous structure of calcium silicate (MCS) with high specific surface area was synthesized using surfactant P123 (triblock copolymer) as template,and its composite films with silk fibroin (SF) were fabricated by solvent-casting method. Fourier transform infrared (FT-IR) spectroscopy analysis showed that random coil and βsheet structure co-existed in the SF films. The bioactivity of the composite film was evaluated by soaking in a simulated body fluid (SBF),and formation of a hydroxycarbonate apatite (HCA) layer was determined by XRD and FESEM. The results showed that the MCS/SF composite film was bioactive as it induced the formation of HCA on the surface of the composite film after soaking in SBF for 7 days. Consequently,the incorporation of MCS into the SF film can enhance the bioactivity of the film,which suggests that the MCS/SF composite film may be a potential biomaterial for bone tissue engineering.
机译：以表面活性剂P123（三嵌段共聚物）为模板，合成了高比表面积的硅酸钙（MCS）的良好介孔结构，并通过溶剂流延法制备了其与丝素蛋白（SF）的复合膜。傅里叶变换红外光谱（FT-IR）分析表明，SF薄膜中同时存在无规卷曲和β片状结构。通过浸泡在模拟体液（SBF）中评估复合膜的生物活性，并通过XRD和FESEM确定碳酸盐磷灰石（HCA）层的形成。结果表明，MCS / SF复合膜在SBF中浸泡7天后可诱导HCA在复合膜表面形成，因此具有生物活性。因此，将MCS掺入SF膜中可以增强其生物活性，这表明MCS / SF复合膜可能是骨组织工程的潜在生物材料。

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