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MEDICAL INTERACTIONS WITH GLASS PACKAGING SURFACES

机译：与玻璃包装表面的药物相互作用

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Recent product recalls in the pharmaceutical industry over the detection of visible glass Hakes (known as delamination) in parcnteral (injectable) products has focused a great deal of attention on glass/product interactions. Because the presence of flakes is often detected after the product has been released to the market, delamination events can result in product recalls and product shortages. If one examines the glass science literature, one will learn that the generation of Hakes from glass surfaces exposed to water-containing environments (known as weathering) is not a new phenomenon, and in fact, the first mention of glass/water interaction was reported in 1770. This paper will look at the mechanism behind the weathering of glass, and describe specific tests that can predict glass/product interactions for glass pharmaceutical containers.
机译：在制药工业中，最近的产品召回涉及检测在对立（可注射）产品中可见玻璃的哈克（称为分层），这引起了人们对玻璃/产品相互作用的极大关注。由于通常会在产品投放市场后检测到薄片的存在，因此分层事件可能导致产品召回和产品短缺。如果研究玻璃科学文献，人们将了解到，暴露于含水环境（称为风化）的玻璃表面产生的“哈克”并不是一种新现象，事实上，据报道首次提到了玻璃与水之间的相互作用。 1770年。本文将研究玻璃耐候性的机制，并描述可以预测玻璃/药物容器的玻璃/产品相互作用的特定测试。

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