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Infrared laser-based sensing in medical applications

机译:医疗应用中基于红外激光的传感

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摘要

Laser-spectroscopic applications in medicine increase in importance. We present two medical applications of laser-based analyses of trace gases. The analysis of exhaled breath concerns the determination of the D/H isotope ratio after intake of a small amount of heavy water. The D/H isotope ratio can be used to deduce the total body water weight and lays the foundation for many other laser-based clinical applications. An elevated D/H ratio could be monitored in breath samples up to 30 days after ingestion of only 5 ml of D_2O. A second example concerns the analysis of surgical smoke produced in minimally invasive laparoscopic surgery with electroknives. The quantitative determination of harmless and hazardous compounds down to the ppm level is demonstrated. A specific example is the presence of sevoflurane at concentrations of 80 to 300 ppm, an anesthetic, which to our knowledge is measured for the first time in an abdominal cavity.
机译:激光光谱在医学中的应用越来越重要。我们介绍了基于激光的痕量气体分析的两种医疗应用。呼气分析涉及摄入少量重水后D / H同位素比的确定。 D / H同位素比可用于推断人体总水重,并为许多其他基于激光的临床应用奠定基础。摄入仅5 ml D_2O后长达30天,呼吸样品中的D / H比可以提高。第二个示例涉及对使用电刀进行的微创腹腔镜手术中产生的手术烟雾的分析。演示了定量分析低至ppm级的无害和有害化合物的方法。一个具体的例子是麻醉剂中浓度为80至300 ppm的七氟醚的存在,据我们所知,这是首次在腹腔中进行测量。

著录项

  • 来源
    《Quantum sensing and nanophotonic devices VII》|2010年|P.760808.1-760808.9|共9页
  • 会议地点 San Francisco CA(US)
  • 作者单位

    ETH Zurich, Institute for Quantum Electronics, Laser Spectroscopy and Sensing Laboratory, Schafmattstrasse 16, CH-8093 Zurich, Switzerland;

    rnEcole Polytechnique Federate de Lausanne (EPFL), Institute of Microengineering (IMT), Photovoltaics and Thin Film Laboratory, Rue A.-L. Breguet 2, CH-2000 Neuchatel, Switzerland;

    rnETH Zurich, Institute for Quantum Electronics, Laser Spectroscopy and Sensing Laboratory, Schafmattstrasse 16, CH-8093 Zurich, Switzerland;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 TP212;
  • 关键词

    laser spectroscopy; breath analysis; deuterated tracers; surgical smoke;

    机译:激光光谱呼吸分析;氘化示踪剂;手术烟雾;

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