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首页> 外文会议>RIAO/OPTILAS 2004 >Laser induced lipolysis on adipose cells
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Laser induced lipolysis on adipose cells

机译：激光诱导脂肪细胞脂解

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摘要

Recently, a new liposuction technique, using a low-level laser (LLL) device and Ultrawet solution prior to the procedure, demonstrated the movement of fat from the inside to the outside of the adipocyte (Neira et al., 2002). To determine the mechanisms involved, we have performed Scanning and Transmission Electron Microscopy studies; Light transmittance measurements on adipocyte dilutions; and a study of laser light propagation in adipose tissue. This studies show; 1. Cellular membrane alterations. 2. LLL is capable to reach the deep adipose tissue layer, and 3. The tumescence solution enhances the light propagation by clearing the tissue. MRI studies demonstrated the appearance of fat on laser treated abdominal tissue. Besides, adipocytes were cultivated and irradiated to observe the effects on isolated cells. These last studies show: 1. 635nm-laser alone is capable of mobilizing cholesterol from the cell membrane; this action is enhanced by the presence of adrenaline and lidocaine. 2. Intracellular fat is released from adipocytes by co joint action of adrenaline, aminophyline and 635nm-laser. Results are consistent with a laser induced cellular process, which causes fat release from the adipocytes into the intercellular space, besides the modification of the cellular membranes.
机译：最近，一种新的抽脂技术，在手术前使用低水平激光（LLL）设备和Ultrawet溶液，证明了脂肪从脂肪细胞内部向外部的运动（Neira等，2002）。为了确定所涉及的机制，我们进行了扫描和透射电子显微镜研究。脂肪细胞稀释液的透光率测量；以及激光在脂肪组织中传播的研究。该研究表明； 1.细胞膜改变。 2. LLL能够到达较深的脂肪组织层，并且3.肿胀溶液通过清除组织来增强光传播。 MRI研究表明，在经过激光治疗的腹部组织上出现了脂肪。此外，培养并照射脂肪细胞以观察其对分离的细胞的作用。这些最新研究表明：1.单独的635nm激光能够从细胞膜中转移胆固醇。肾上腺素和利多卡因的存在会增强这种作用。 2.通过肾上腺素，氨基茶碱和635nm激光的共同作用从脂肪细胞释放细胞内脂肪。结果与激光诱导的细胞过程一致，该过程导致脂肪从脂肪细胞释放到细胞间空间，除了细胞膜的修饰。

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