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Knowledge and productivity in the pharmaceutical industry

机译:制药行业的知识和生产力

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Pharmaceutical firms perform Ru00026;D to develop and maintain core knowledge and capabilities. They use foundational knowledge to identify and evaluate relevant scientific advances and integrate those advances with existing knowledge and capabilities throughout the innovation pipeline. If core scientific knowledge and technical capabilities are used in this manner to increase innovative productivity by decreasing the use of other inputs, conventional measures of productivity based solely on outputs, per unit time, are likely to be inaccurate. We analyze productivity by examining development time and controlling for knowledge inputs. This approach measures the effect of core knowledge generated through pre-clinical laboratory Ru00026;D on development time in later stages of clinical development. We use patents and citations to model the use of technical knowledge generated through pre-clinical laboratory research in subsequent clinical development activities. Our results indicate that internally generated knowledge and patents, which builds on the existing scientific base are associated with shorter development times.
机译:制药公司执行Ru00026; D来开发和维护核心知识和能力。他们使用基础知识来识别和评估相关的科学进步,并将这些进步与整个创新流程中的现有知识和能力整合在一起。如果以此方式利用核心科学知识和技术能力通过减少对其他投入的使用来提高创新生产率,那么仅基于产出的单位时间的常规生产率度量可能会不准确。我们通过检查开发时间并控制知识输入来分析生产力。这种方法测量了临床前实验室Ru00026; D生成的核心知识对临床开发后期阶段开发时间的影响。我们使用专利和引用来模拟通过临床前实验室研究在随后的临床开发活动中产生的技术知识。我们的结果表明,基于现有科学基础的内部产生的知识和专利与较短的开发时间相关。

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