• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>The Second Asian symposium on pharmaceutical sciences and technology >Nanostructured lipid carriers (NLC) loaded zedoary turmeric oil for parenteral drug delivery: preparation and in vitro evaluation
【24h】

Nanostructured lipid carriers (NLC) loaded zedoary turmeric oil for parenteral drug delivery: preparation and in vitro evaluation

机译：载有纳米结构脂质载体（NLC）的Zedoary姜黄油用于肠胃外给药：制备和体外评估

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: The objective of the present work was to study the preparation and characteristics of Zedoary Turmeric Oil (ZTO), a Traditional Chinese oily Medicine, loaded nanostructured lipid carriers (NLC); Methods: Aqueous dispersions of NLC were successfully prepared by melt-emulsification technique. Properties of NLC such as the particle size and its distribution, the Transmission Electron Microscope (TEM), drug entrapment efficiency and drug release behavior were investigated, respectively; Results: The results indicated the prepared NLC could enhance the drug release rate over the SLN, and the drug release rate could be adjusted by the liquid lipid content in lipid nanospheres; Conclusion: the presented NLC system might be a promising intravenous dosage form of water-insoluble oily drugs.
机译：目的：本研究的目的是研究负载了纳米结构脂质载体（NLC）的中草药油姜黄姜黄油（ZTO）的制备和特性。方法：采用熔融乳化技术成功制备了NLC水分散体。研究了NLC的性质，如粒径和分布，透射电子显微镜（TEM），药物截留效率和药物释放行为。结果：结果表明，所制备的NLC比SLN具有更高的释药速率，并且可以通过脂质纳米球中的液体脂质含量来调节释药速率。结论：提出的NLC系统可能是水不溶性油性药物的有希望的静脉剂型。

著录项

  • 来源
  • 会议地点 Xian(CN)
  • 作者

    Xiuli Zhao; Kailiang Yang; Mingxi Qiao; Haiyang Hu; Dawei Chen;

  • 作者单位

    Department of Pharmaceutics, School of Pharmaceutical Science, Shenyang Pharmaceutical University, No.103, WenhuaRoad, Shenyang 110016, China;

    Department of Pharmaceutics, School of Pharmaceutical Science, Shenyang Pharmaceutical University, No.103, WenhuaRoad, Shenyang 110016, China;

    Department of Pharmaceutics, School of Pharmaceutical Science, Shenyang Pharmaceutical University, No.103, WenhuaRoad, Shenyang 110016, China;

    Department of Pharmaceutics, School of Pharmaceutical Science, Shenyang Pharmaceutical University, No.103, WenhuaRoad, Shenyang 110016, China;

    Department of Pharmaceutics, School of Pharmaceutical Science, Shenyang Pharmaceutical University, No.103, WenhuaRoad, Shenyang 110016, China;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药剂学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号