首页> 外文会议>Society for Biomaterials Transaction of the 31st Annual Meeting vol.XXIX pt.2 >Effects of Nanoscale Pore Size and Microscale Particle Size on Diffusion of Proteinase K out of Sol-Gel Silica
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Effects of Nanoscale Pore Size and Microscale Particle Size on Diffusion of Proteinase K out of Sol-Gel Silica

机译:纳米级孔径和微米级粒度对溶胶-凝胶二氧化硅中蛋白酶K扩散的影响

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摘要

Silica xerogels, with the lowest overall porosity and largest pores showed the highest retention, highest amount of enzyme released, and the fastest release rates compared to silica aerogels and ambigels. The enzyme release rate is inversely proportional to particle size and directly proportional to incubation temperature. The emulsion method also showed better retention of enzyme compared to the ground samples. Recent data (not yet finalized) suggests that the microstructure of xerogels do a better job at stabilizing the enzyme than ambigels and aerogels.
机译:与二氧化硅气凝胶和含气凝胶相比,具有最低总体孔隙率和最大孔隙的二氧化硅气凝胶显示出最高的保留率,最大的酶释放量和最快的释放速率。酶的释放速率与粒径成反比,与孵育温度成正比。与研磨样品相比,乳液法还显示出更好的酶保留能力。最新数据(尚未最终确定)表明,干凝胶的微观结构在稳定酶方面比环糊剂和气凝胶做得更好。

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