首页> 外文会议>Society for Biomaterials Transaction Annual Meeting vol.29 pt.2 >Effect of modified stainless steel 316L substrates on 3T3 fibroblast cell attachment
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Effect of modified stainless steel 316L substrates on 3T3 fibroblast cell attachment

机译:改性316L不锈钢衬底对3T3成纤维细胞附着的影响

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We have successfully formed ordered self assembled monolayers of phosphonic and carboxylic acids with different tail terminus on stainless steel substrates. Cell experiments with 3T3 fibroblast cells have shown that fewer cells attach to methyl terminated SAMs compared to the hydrophilic groups. We conclude from our experiments on 3T3 fibroblasts that octadecylphosphonic acid and stearic acid are better candidates than amine, hydroxyl and carboxylic acid to prevent cell attachment on stents.
机译:我们已经成功地在不锈钢基板上形成了具有不同尾端的有序膦酸和羧酸自组装单层膜。用3T3成纤维细胞进行的细胞实验表明,与亲水基团相比,与甲基封端的SAM连接的细胞更少。从我们在3T3成纤维细胞上进行的实验得出的结论是,十八烷基膦酸和硬脂酸比胺,羟基和羧酸更好的候选物,可防止细胞附着在支架上。

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