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首页> 外文会议>Society of Tribologists and Lubrication Engineers annual meeting amp; exhibition 2009 >POROUS UHMWPE SCAFFOLDS IMPREGNATED WITH BIO-DERIVED MATERIALS: A NEW CLASS OF ORTHOPAEDIC MATERIAL
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POROUS UHMWPE SCAFFOLDS IMPREGNATED WITH BIO-DERIVED MATERIALS: A NEW CLASS OF ORTHOPAEDIC MATERIAL

机译：浸有生物衍生材料的多孔超高分子量聚乙烯脚手架：一类新型的骨科材料

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摘要

Ultra high molecular weight polyethylene (UHMWPE) is the most commonly used bearing material used domestically in total-joint implants. This polymer finds use because of its high resistance to wear, its mechanical properties and its inertness as a bulk material in vivo. However, debris generated during wear of UHMWPE leads to the fundamental limiting factor in the devices, osteolysis. This immune system response to the polymer wear debris leads to gradual loss of periprosthetic bone leading to potential slippage of the implant or bone fractures [1]. The primary tactic of researchers to address this topic has been to reduce the wear rate of UHMWPE. This has been largely accomplished in recent years by irradiation crosslinking of the polymer [2-5]. Crosslinking can, however, negatively impact other mechanical properties that are important in orthopaedic devices, such as yield strength and impact toughness. Another approach to the problem of osteolysis, rather than strict reduction of the volume of wear debris, may be the use of bearing materials that produce wear debris that does not incite such an immune response.
机译：超高分子量聚乙烯（UHMWPE）是国内在全关节植入物中最常用的轴承材料。由于该聚合物具有高的耐磨性，机械性能以及其作为体内本体材料的惰性，因此得到了使用。但是，UHMWPE磨损期间产生的碎屑会导致设备的根本限制因素，即骨溶解。这种对聚合物磨损碎片的免疫系统反应会导致假体周围骨的逐渐丢失，从而导致植入物可能滑移或骨折[1]。研究人员解决这个问题的主要策略是降低UHMWPE的磨损率。近年来，这是通过聚合物[2-5]的辐射交联而在很大程度上完成的。但是，交联会负面影响矫形设备中重要的其他机械性能，例如屈服强度和冲击韧性。解决溶骨问题的另一种方法，而不是严格减少磨损碎屑的体积，可以是使用产生不会引起这种免疫反应的磨损碎屑的轴承材料。

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