A Highly Sensitive and Selective Surface-Enhanced Nanobiosensor

机译：高灵敏度和选择性表面增强纳米生物传感器。

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Nanosphere lithography (NSL) derived triangular Ag nanoparticles were used to create an extremely sensitive and specific optical biological and chemical nanosensor. Using simple UV-vis spectroscopy, biotinylated surface-confined Ag nanoparticles were used to detect streptavidin down to one picomolar concentrations. The system was tested for nonspecific binding interactions with bovine serum albumin and was found to display virtually no adverse results. The extremely sensitive and selective response of the Ag nanoparticle sensor indicates an exciting use for biological and chemical sensing.

机译：纳米球光刻（NSL）衍生的三角形银纳米颗粒用于创建极其敏感和特异的光学生物和化学纳米传感器。使用简单的紫外-可见光谱，使用生物素化的表面受限的银纳米颗粒检测链霉亲和素的浓度低至一个皮摩尔。测试了该系统与牛血清白蛋白的非特异性结合相互作用，发现该系统几乎没有不良结果。 Ag纳米颗粒传感器的极度敏感和选择性的响应表明其在生物和化学传感方面的令人兴奋的用途。

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《Symposium on Molecularly Imprinted Materials―Sensors and Other Devices, Apr 2-5, 2002, San Francisco, California》|2002年|p.133-138|共6页
会议地点 San Francisco CA(US);San Francisco CA(US)
作者
Amanda J. Haes; Richard P. Van Duyne;
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作者单位

Department of Chemistry, Northwestern University, Evanston, IL 60208-3113, USA;

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原文格式 PDF
正文语种 eng
中图分类化学工业;
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8. Highly Sensitive and Selective Surface-Enhanced Nanobiosensor. [R] . Haes, A. J., Van Duyne, R. P. 2002

机译：高灵敏度和选择性表面增强纳米生物传感器。

A Highly Sensitive and Selective Surface-Enhanced Nanobiosensor

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