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Accelerated Chemical Reactions for Lab-on-a-Chip Applications Using Electrowetting-Induced Droplet Self-Oscillations

机译:使用电润湿诱导的液滴自激振荡加速芯片实验室应用的化学反应

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Self-oscillation induced by electrowetting can be easily produced by inserting an electrode into a droplet and applying a square-wave electrical signal. We anticipated that this effect can be used to speed up mixing and reaction of components in small droplets. Several different chemical systems were used to verify this acceleration. Indeed, the mixing rate was enhanced by factors of 15 to 100 relative to that of passive diffusion. In the experiments reported herein, we used flat, hydrophobic silicon substrates. This effect can be further improved using surfaces covered with nanograss, i.e.; dense arrays of high-aspect ratio nano/micro-pillars whose morphology renders the surface swperhydrophobic. Such surfaces will be useful in integrating droplet mixing with other techniques of droplet microfluidics for lab-on-a-chip applications.
机译:通过将电极插入液滴中并施加方波电信号,可以轻松地产生由电润湿引起的自激。我们预计,这种作用可用于加速小液滴中组分的混合和反应。使用了几种不同的化学系统来验证这种加速。实际上,相对于被动扩散,混合速率提高了15到100倍。在本文报道的实验中,我们使用了平坦的疏水性硅基板。使用覆盖有纳米草的表面可以进一步改善该效果。高纵横比纳米/微柱的密集阵列,其形态使表面呈疏水性。这样的表面将在将液滴混合与其他液滴微流体技术整合到芯片实验室应用中将是有用的。

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