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Visual Haptic-Based Biomolecular Docking and Its Applications in E-Learning

机译:基于视觉触觉的生物分子对接及其在电子学习中的应用

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Visual haptic-based biomolecular docking systems could be used for both research and e-learning in research intensive disciplines such as biology, physical chemistry, molecular medicine, biophysics, structural biology, bioinformatics, etc. The assembly of molecules in a three-dimensional space or molecular docking is used for rational drug design where a ligand docks onto a receptor. The computer-aided design systems allow a real-time interactive visualization and manipulation of molecules in virtual environment. These techniques help the user to understand molecular interactions. In recent years, besides the visualization techniques, there has been increasing interest in using haptic interfaces to facilitate the exploration and analysis of molecular docking. Haptic device enables the users to manipulate the molecules and feel its interaction during the docking process in virtual experiment on computer. In this paper, we describe a visual haptic-based biomolecular docking system that we developed for research in helix-helix docking and propose its application in e-learning. We also describe haptic-based collaborative e-learning scenarios.
机译:基于视觉触觉的生物分子对接系统可用于研究密集型学科的研究和电子学习,例如生物学,物理化学,分子医学,生物物理学,结构生物学,生物信息学等。在三维空间中组装分子分子对接或分子对接用于合理的药物设计,其中配体对接在受体上。计算机辅助设计系统允许在虚拟环境中实时交互可视化和操纵分子。这些技术可帮助用户了解分子相互作用。近年来,除了可视化技术外,人们对使用触觉界面来促进分子对接的探索和分析也越来越感兴趣。触觉设备使用户能够在计算机上进行虚拟实验的对接过程中操纵分子并感受其相互作用。在本文中,我们描述了一个基于视觉触觉的生物分子对接系统,该系统是我们为研究螺旋-螺旋对接而开发的,并提出了其在电子学习中的应用。我们还将描述基于触觉的协作式电子学习方案。

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