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首页> 外文会议>Village chickens, poverty alleviation and the sustainable control of newcastle disease >Evaluation of the cold chain encountered by 'wet' I-2 Newcastle disease vaccine from the vaccine production department to the village chicken in Mozambique
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Evaluation of the cold chain encountered by 'wet' I-2 Newcastle disease vaccine from the vaccine production department to the village chicken in Mozambique

机译：评估“湿” I-2新城疫疫苗从疫苗生产部门到莫桑比克乡村鸡所遇到的冷链

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摘要

Live vaccines are biological products that must be stored away from excess heat, cold or light to ensure maximum potency. The only way to ensure the appropriate conditions for vaccine storage and transport is to have a functional and validated cold chain. However, in developing countries such as Mozambique, maintenance of the cold chain and conservation of vaccines present many challenges. 1-2 Newcastle disease (ND) vaccine is ideal for such situations since it can be stored outside refrigeration for short periods, using simple methods that are within the resources of community vaccinators.rnThe vaccine cold chain encountered by 'wet' 1-2 ND vaccine in Mozambique was described and evaluated using data loggers. It was found that the cold chain is composed of four major stages, namely 1. Veterinary Research National Institute in Maputo, 2. storage at the Provincial Livestock Services, 3. District Directorate of Agriculture and 4. community vaccinator.rnThe vaccine cold chain in Mozambique can be divided into the 'conventional cold chain' and the 'non-conventional' cold chain. The temperatures in the 'conventional cold chain' (refrigerators and cold rooms, domestic refrigerators, and insulated boxes with icepacks used for distribution of vaccine) were sometimes outside the recommended range of 2-8 ℃. The main factors responsible for this were the poor handling and monitoring procedures, and inappropriate equipment.rnThe temperatures in the 'non-conventional cold chain' (storage of vaccine in a cool place in the home of the community vaccinator, and transport wrapped in a damp cloth in an open-weave basket during vaccination) were below 29 ℃, except where synthetic bags were used for vaccine transport.
机译：活疫苗是生物产品，必须远离过多的热，冷或光保存，以确保最大效力。确保疫苗储存和运输的适当条件的唯一方法是拥有功能齐全且经过验证的冷链。但是，在莫桑比克等发展中国家，维持冷链和保存疫苗提出了许多挑战。 1-2新城疫（ND）疫苗是此类情况的理想选择，因为它可以使用社区疫苗接种者资源范围内的简单方法在冷藏室外短期存放.rn'湿'1-2 ND遇到的疫苗冷链描述了莫桑比克的疫苗并使用数据记录仪进行了评估。发现冷链由四个主要阶段组成，即1.马普托兽医研究所，2。省畜牧服务局的储存，3。农业区局和4.社区疫苗接种者。莫桑比克可分为“常规冷链”和“非常规”冷链。 “常规冷链”（冰箱和冷藏室，家用冰箱以及装有疫苗的用于冰袋的保温箱）中的温度有时超出建议的2-8℃。造成这种情况的主要原因是不良的处理和监测程序以及不适当的设备。rn“非常规冷链”中的温度（疫苗储存在社区疫苗接种者家中阴凉的地方，运输包装在疫苗接种期间，用开放式编织篮中的湿布）低于29℃，除非使用合成袋运输疫苗。

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  • 会议地点 Dar es Salaam(TZ)
  • 作者

    Manuel Chicamisse; Mohamed Harun; Robyn G. Alders; Mary Young;

  • 作者单位

    Provincial Livestock Services, Beira, Sofala Province, Mozambique;

    Southern Africa Newcastle Disease Control Project, GRM International, C.P. 1168, Maputo, Mozambique Faculty of Veterinary Medicine, University of Eduardo Mondlane, Maputo, Mozambique;

    Southern Africa Newcastle Disease Control Project, GRM International, C.P. 1168, Maputo, Mozambique International Rural Poultry Centre, KYEEMA Foundation, GPO Box 3023, Brisbane, Queensland 4001, Australia and International Veterinary Medicine Program, Tufts Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA;

    Southern Africa Newcastle Disease Control Project, GRM International, C.P. 1168, Maputo, Mozambique International Rural Poultry Centre, KYEEMA Foundation, GPO Box 3023, Brisbane, Queensland 4001, Australi;

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